Congenital hyperinsulinism: current trends in diagnosis and therapy

JB Arnoux, V Verkarre, C Saint-Martin… - Orphanet journal of rare …, 2011 - Springer
Congenital hyperinsulinism (HI) is an inappropriate insulin secretion by the pancreatic β-
cells secondary to various genetic disorders. The incidence is estimated at 1/50, 000 live …

Knowledge gaps and research needs for understanding and treating neonatal hypoglycemia: workshop report from Eunice Kennedy Shriver National Institute of Child …

WW Hay, TNK Raju, RD Higgins, SC Kalhan… - The Journal of …, 2009 - jpeds.com
Maintenance of glucose homeostasis via initiation of glucose production is one of the critical
physiological events that results in a smooth transition and adaptation to extrauterine life. A …

Association of neonatal glycemia with neurodevelopmental outcomes at 4.5 years

CJD McKinlay, JM Alsweiler, NS Anstice… - JAMA …, 2017 - jamanetwork.com
Importance Hypoglycemia is common during neonatal transition and may cause permanent
neurological impairment, but optimal intervention thresholds are unknown. Objective To test …

Patterns of cerebral injury and neurodevelopmental outcomes after symptomatic neonatal hypoglycemia

CM Burns, MA Rutherford, JP Boardman… - Pediatrics, 2008 - publications.aap.org
BACKGROUND. Symptomatic neonatal hypoglycemia may be associated with later
neurodevelopmental impairment. Brain injury patterns identified on early MRI scans and …

Impact of glucose metabolism on the develo** brain

M Cacciatore, EA Grasso, R Tripodi… - Frontiers in …, 2022 - frontiersin.org
Glucose is the most important substrate for proper brain functioning and development, with
an increased glucose consumption in relation to the need of creating new brain structures …

[HTML][HTML] Hypoglycemia in the preterm neonate: etiopathogenesis, diagnosis, management and long-term outcomes

A Sharma, A Davis, PS Shekhawat - Translational pediatrics, 2017 - ncbi.nlm.nih.gov
Glucose, like oxygen, is of fundamental importance for any living being and it is the major
energy source for the fetus and the neonate during gestation. The placenta ensures a steady …

Hypoglycemia is associated with increased risk for brain injury and adverse neurodevelopmental outcome in neonates at risk for encephalopathy

EWY Tam, LA Haeusslein, SL Bonifacio, HC Glass… - The Journal of …, 2012 - Elsevier
OBJECTIVE: To investigate the contribution of hypoglycemia in the first 24 hours after birth to
brain injury in term newborns at risk for neonatal encephalopathy. STUDY DESIGN: A …

Neonatal hypoglycemia and brain vulnerability

LC De Angelis, G Brigati, G Polleri, M Malova… - Frontiers in …, 2021 - frontiersin.org
Neonatal hypoglycemia is a common condition. A transient reduction in blood glucose
values is part of a transitional metabolic adaptation following birth, which resolves within the …

The effect of type 1 diabetes on the develo** brain

FJ Cameron, EA Northam, CM Ryan - The Lancet Child & Adolescent …, 2019 - thelancet.com
The effect of type 1 diabetes on the develo** brain is a topic of primary research interest. A
variety of potential dysglycaemic insults to the brain can cause cellular and structural injury …

Occipital lobe injury and cortical visual outcomes after neonatal hypoglycemia

EWY Tam, E Widjaja, SI Blaser, DL MacGregor… - …, 2008 - publications.aap.org
OBJECTIVES. Hypoglycemia is a significant problem in neonates, and a pattern of
parietooccipital diffusion restriction on MRI scans has been reported. The purpose of this …