Digital twins for tissue culture techniques—concepts, expectations, and state of the art
Techniques to provide in vitro tissue culture have undergone significant changes during the
last decades, and current applications involve interactions of cells and organoids, three …
last decades, and current applications involve interactions of cells and organoids, three …
Single-cell infrared microspectroscopy quantifies dynamic heterogeneity of mesenchymal stem cells during adipogenic differentiation
Y Wang, W Dai, Z Liu, J Liu, J Cheng, Y Li, X Li… - Analytical …, 2020 - ACS Publications
The central relevance of cellular heterogeneity to biological phenomena raises the rational
needs for analytical techniques with single-cell resolution. Here, we developed a single-cell …
needs for analytical techniques with single-cell resolution. Here, we developed a single-cell …
Coupling of P2Y receptors to Ca2+ mobilization in mesenchymal stromal cells from the human adipose tissue
PD Kotova, MF Bystrova, OA Rogachevskaja… - Cell Calcium, 2018 - Elsevier
The purinergic transduction was examined in mesenchymal stromal cells (MSCs) from the
human adipose tissue, and several nucleotides, including ATP, UTP, and ADP, were found …
human adipose tissue, and several nucleotides, including ATP, UTP, and ADP, were found …
Heterogeneous structure of stem cells dynamics: statistical models and quantitative predictions
Understanding stem cell (SC) population dynamics is essential for develo** models that
can be used in basic science and medicine, to aid in predicting cells fate. These models can …
can be used in basic science and medicine, to aid in predicting cells fate. These models can …
Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity
Z Hamidouche, K Rother, J Przybilla, A Krinner… - Stem Cells, 2017 - academic.oup.com
The molecular mechanisms by which heterogeneity, a major characteristic of stem cells, is
achieved are yet unclear. We here study the expression of the membrane stem cell antigen …
achieved are yet unclear. We here study the expression of the membrane stem cell antigen …
In vivo, in vitro, in silico: computational tools for product and process design in tissue engineering
L Geris - Computational Modeling in Tissue Engineering, 2012 - Springer
This chapter aims to provide an introduction to how engineering tools in general and
computational models in particular can contribute to advancing the tissue engineering (TE) …
computational models in particular can contribute to advancing the tissue engineering (TE) …
[PDF][PDF] Digital twins for tissue culture techniques—concepts, expectations, and state of the art. Processes 2021; 9: 447
Techniques to provide in vitro tissue culture have undergone significant changes during the
last decades, and current applications involve interactions of cells and organoids, three …
last decades, and current applications involve interactions of cells and organoids, three …
Calcium signaling initiated by agonists in mesenchymal stromal cells from the human adipose tissue
PD Kotova, OA Rogachevskaja… - Calcium and Signal …, 2018 - books.google.com
Mesenchymal stromal cells (MSCs) from different sources represent a heterogeneous
population of proliferating non-differentiated cells that contain multipotent stem cells capable …
population of proliferating non-differentiated cells that contain multipotent stem cells capable …
cGMP-dependent protein kinase modulates the sensitivity of mesenchymal stromal cells to purinergic agonists
EN Kochkina, PD Kotova, NI Enukashvily… - … ), Supplement Series A …, 2019 - Springer
Calcium signaling induced by ATP in mesenchymal stromal cells (MSCs) from the human
adipose tissue was studied by using the Ca 2+ dye Fluo-4 and Ca 2+ imaging. Previously …
adipose tissue was studied by using the Ca 2+ dye Fluo-4 and Ca 2+ imaging. Previously …
Computational Models of Spatio-temporal Stem Cell Organization
P Buske, J Galle - Stem Cell Biology and Regenerative Medicine, 2022 - taylorfrancis.com
A main objective of computational modeling approaches to stem cell organization is to
provide a general and predictive model framework that links observable phenomena on the …
provide a general and predictive model framework that links observable phenomena on the …