Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

New technologies for the purification of stable membrane proteins have emerged in recent
years, in particular methods that allow the preparation of membrane proteins with their …

Once removed from their natural environment, membrane proteins depend on membrane‐
mimetic systems to retain their native structures and functions. To this end, lipid‐bilayer …

For some membrane proteins, detergent-mediated solubilization compromises protein
stability and functionality, often impairing biophysical and structural analyses. Hence …

The use of styrene–maleic acid (SMA) copolymers to extract and purify transmembrane
proteins, while retaining their native bilayer environment, overcomes many of the …

The fundamental importance of membrane proteins in drug discovery has meant that
membrane mimetic systems for studying membrane proteins are of increasing interest. One …

Membrane proteins usually need to be extracted from their native environment and
separated from other membrane components for in-depth in vitro characterization. The use …

Biological characterisation of membrane proteins lags behind that of soluble proteins. This
reflects issues with the traditional use of detergents for extraction, as the surrounding lipids …

Solubilisation of biological lipid bilayer membranes for analysis of their protein complement
has traditionally been carried out using detergents, but there is increasing interest in the use …

Lipid-bilayer nanodiscs provide a stable, native-like membrane environment for the
functional and structural studies of membrane proteins and other membrane-binding …