The 5th edition of this indispensable resource captures the latest insights in neonatal
neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Children surviving preterm birth have a high risk of disability, particularly cognitive and
learning problems. There is extensive clinical and experimental evidence that disability is …

Objective: Therapeutic hypothermia reduces cerebral injury and improves the neurological
outcome secondary to hypoxic ischemic encephalopathy in newborns. It has been indicated …

Neonatal hypoxic ischemic encephalopathy (HIE) is a common disease caused by perinatal
asphyxia, a major cause of neonatal death, neurological behavior, and long-term disability …

The role of cytokines in the pathogenesis of brain injury and their relation to neurological
outcomes of asphyxiated neonates is not fully defined. We hypothesize that interleukin-1 …

Perinatal brain damage has been implicated in the pathogenesis of neurodevelopmental
impairments and psychiatric illnesses. This article reviews evidence that infection outside of …

In term neonatal encephalopathy, little is known about the relationship between early
inflammatory markers, neonatal brain injury, and long-term neurodevelopmental outcome …

Insults to the develo** brain often result in irreparable damage resulting in long-term
deficits in motor and cognitive functions. The only treatment today for hypoxic-ischemic …

AIM: To examine the dynamic changes of TNF-α, IL-6, IL-10, and GDNF (glial cell-derived
neurotrophic factor) in serum or brain tissues of neonatal rat with hypoxic-ischemic …