From childhood adversity to latent stress vulnerability in adulthood: the mediating roles of sleep disturbances and HPA axis dysfunction

L Simon, R Admon - Neuropsychopharmacology, 2023 - nature.com
Childhood adversity is a prominent predisposing risk factor for latent stress vulnerability,
expressed as an elevated likelihood of develo** stress-related psychopathology upon …

Stress and substance use disorders: risk, relapse, and treatment outcomes

R Sinha - The Journal of Clinical Investigation, 2024 - jci.org
Stress has long been associated with substance misuse and substance use disorders
(SUDs). The past two decades have seen a surge in research aimed at understanding the …

The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis

DNS Senaratne, B Thakkar, BH Smith, TG Hales… - BMC medicine, 2024 - Springer
Abstract Background Adverse childhood experiences (ACEs) have been implicated in the
aetiology of a range of health outcomes, including multimorbidity. In this systematic review …

[HTML][HTML] Childhood abuse and neglect, and mortality risk in adulthood: A systematic review and meta-analysis

S D'arcy-Bewick, A Terracciano, N Turiano… - Child Abuse & …, 2022 - Elsevier
Background Research findings on the relationship between childhood abuse and neglect
(CAN) and mortality risk in adulthood are inconsistent. Objective To examine the association …

[HTML][HTML] Noradrenergic alterations associated with early life stress

M Sheppard, J Rasgado-Toledo, N Duncan… - Neuroscience & …, 2024 - Elsevier
Significant stress in childhood or adolescence is linked to both structural and functional
changes in the brain in human and analogous animal models. In addition, neuromodulators …

Psychological risk factors and cardiovascular disease

V Carola, C Vincenzo, G Di Vincenzo, C Morale… - Frontiers in …, 2024 - frontiersin.org
Objectives Cardiovascular diseases (CVDs) are a leading cause of death worldwide,
emerging from a combination of several factors. The aim of this review is to define the …

Annual Research Review: Map** the multifaceted approaches and impacts of adverse childhood experiences–an umbrella review of meta‐analyses

B Kim, M Royle - Journal of Child Psychology and Psychiatry, 2024 - Wiley Online Library
Adverse childhood experiences (ACEs) significantly impact lifelong health and well‐being.
Despite extensive research, a comprehensive understanding of ACEs' multifaceted impacts …

Childhood maltreatment and risk of endocrine diseases: an exploration of mediating pathways using sequential mediation analysis

S Wen, J Zhu, X Han, Y Li, H Liu, H Yang, C Hou, S Xu… - BMC medicine, 2024 - Springer
Abstract Background Adverse childhood experiences (ACEs), including childhood
maltreatment, have been linked with increased risk of diabetes and obesity during …

Blunted neurobiological reactivity and attentional bias to threat underlie stress-related disorders in women survivors of intimate partner violence

X Goldberg, C Espelt, R Nadal, Y Alon… - Psychological …, 2023 - cambridge.org
BackgroundIntimate partner violence (IPV) alters women's neurobiological stress response
systems. We propose that individual differences early in the attentional processing of threats …

Early life stress in women with autoimmune thyroid disorders

A Corso, H Engel, F Müller, S Fiacco, L Mernone… - Scientific Reports, 2023 - nature.com
Autoimmune thyroid disorders (AITD) represent the most frequent of all autoimmune
disorders. Their aetiopathogenesis is incompletely understood, but most likely multifactorial …