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From childhood adversity to latent stress vulnerability in adulthood: the mediating roles of sleep disturbances and HPA axis dysfunction
Childhood adversity is a prominent predisposing risk factor for latent stress vulnerability,
expressed as an elevated likelihood of develo** stress-related psychopathology upon …
expressed as an elevated likelihood of develo** stress-related psychopathology upon …
Stress and substance use disorders: risk, relapse, and treatment outcomes
R Sinha - The Journal of Clinical Investigation, 2024 - jci.org
Stress has long been associated with substance misuse and substance use disorders
(SUDs). The past two decades have seen a surge in research aimed at understanding the …
(SUDs). The past two decades have seen a surge in research aimed at understanding the …
The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis
Abstract Background Adverse childhood experiences (ACEs) have been implicated in the
aetiology of a range of health outcomes, including multimorbidity. In this systematic review …
aetiology of a range of health outcomes, including multimorbidity. In this systematic review …
[HTML][HTML] Childhood abuse and neglect, and mortality risk in adulthood: A systematic review and meta-analysis
Background Research findings on the relationship between childhood abuse and neglect
(CAN) and mortality risk in adulthood are inconsistent. Objective To examine the association …
(CAN) and mortality risk in adulthood are inconsistent. Objective To examine the association …
[HTML][HTML] Noradrenergic alterations associated with early life stress
Significant stress in childhood or adolescence is linked to both structural and functional
changes in the brain in human and analogous animal models. In addition, neuromodulators …
changes in the brain in human and analogous animal models. In addition, neuromodulators …
Psychological risk factors and cardiovascular disease
V Carola, C Vincenzo, G Di Vincenzo, C Morale… - Frontiers in …, 2024 - frontiersin.org
Objectives Cardiovascular diseases (CVDs) are a leading cause of death worldwide,
emerging from a combination of several factors. The aim of this review is to define the …
emerging from a combination of several factors. The aim of this review is to define the …
Annual Research Review: Map** the multifaceted approaches and impacts of adverse childhood experiences–an umbrella review of meta‐analyses
B Kim, M Royle - Journal of Child Psychology and Psychiatry, 2024 - Wiley Online Library
Adverse childhood experiences (ACEs) significantly impact lifelong health and well‐being.
Despite extensive research, a comprehensive understanding of ACEs' multifaceted impacts …
Despite extensive research, a comprehensive understanding of ACEs' multifaceted impacts …
Childhood maltreatment and risk of endocrine diseases: an exploration of mediating pathways using sequential mediation analysis
Abstract Background Adverse childhood experiences (ACEs), including childhood
maltreatment, have been linked with increased risk of diabetes and obesity during …
maltreatment, have been linked with increased risk of diabetes and obesity during …
Blunted neurobiological reactivity and attentional bias to threat underlie stress-related disorders in women survivors of intimate partner violence
BackgroundIntimate partner violence (IPV) alters women's neurobiological stress response
systems. We propose that individual differences early in the attentional processing of threats …
systems. We propose that individual differences early in the attentional processing of threats …
Early life stress in women with autoimmune thyroid disorders
A Corso, H Engel, F Müller, S Fiacco, L Mernone… - Scientific Reports, 2023 - nature.com
Autoimmune thyroid disorders (AITD) represent the most frequent of all autoimmune
disorders. Their aetiopathogenesis is incompletely understood, but most likely multifactorial …
disorders. Their aetiopathogenesis is incompletely understood, but most likely multifactorial …