Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options
D Liu, SY Huang, JH Sun, HC Zhang, QL Cai… - Military Medical …, 2022 - Springer
Sepsis is a common complication of combat injuries and trauma, and is defined as a life-
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
Electrochemical biosensors for whole blood analysis: recent progress, challenges, and future perspectives
S Li, H Zhang, M Zhu, Z Kuang, X Li, F Xu… - Chemical …, 2023 - ACS Publications
Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …
health management and disease monitoring. Over the past 10 years, advances in …
B cell depletion therapies in autoimmune disease: advances and mechanistic insights
DSW Lee, OL Rojas, JL Gommerman - Nature reviews Drug discovery, 2021 - nature.com
In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …
Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas
The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …
host response to infection. In sepsis, the immune response that is initiated by an invading …
Cytokine storm and sepsis disease pathogenesis
Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical
syndrome related to the host response to infection. The severity of infections is due to an …
syndrome related to the host response to infection. The severity of infections is due to an …
Advances in the understanding and treatment of sepsis-induced immunosuppression
F Venet, G Monneret - Nature Reviews Nephrology, 2018 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. Sepsis can induce acute kidney injury and multiple organ failures …
host response to infection. Sepsis can induce acute kidney injury and multiple organ failures …
Current gaps in sepsis immunology: new opportunities for translational research
Increasing evidence supports a central role of the immune system in sepsis, but the current
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …
GM-CSF, IL-3, and IL-5 family of cytokines: regulators of inflammation
M Dougan, G Dranoff, SK Dougan - Immunity, 2019 - cell.com
The β common chain cytokines GM-CSF, IL-3, and IL-5 regulate varied inflammatory
responses that promote the rapid clearance of pathogens but also contribute to pathology in …
responses that promote the rapid clearance of pathogens but also contribute to pathology in …