From squiggle to basepair: computational approaches for improving nanopore sequencing read accuracy
Nanopore sequencing is a rapidly maturing technology delivering long reads in real time on
a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this …
a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this …
Codon usage and tRNA content in unicellular and multicellular organisms.
T Ikemura - Molecular biology and evolution, 1985 - academic.oup.com
Choices of synonymous codons in unicellular organisms are here reviewed, and differences
in synonymous codon usages between Escherichia coli and the yeast Saccharomyces …
in synonymous codon usages between Escherichia coli and the yeast Saccharomyces …
The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications
A simple, effective measure of synonymous codon usage bias, the Codon Adaptation Index,
is detailed. The index uses a reference set of highly expressed genes from a species to …
is detailed. The index uses a reference set of highly expressed genes from a species to …
The 'effective number of codons' used in a gene
F Wright - Gene, 1990 - Elsevier
A simple measure is presented that quantifies how far the codon usage of a gene departs
from equal usage of synonymous codons. This measure of synonymous codon usage bias …
from equal usage of synonymous codons. This measure of synonymous codon usage bias …
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
JC Lee, JT Laydon, PC McDonnell, TF Gallagher… - Nature, 1994 - nature.com
Production of interleukin-1 and tumour necrosis factor from stimulated human monocytes is
inhibited by a new series of pyridinyl-imidazole compounds. Using radiolabelled and radio …
inhibited by a new series of pyridinyl-imidazole compounds. Using radiolabelled and radio …
A comprehensive set of sequence analysis programs for the VAX
J Devereux, P Haeberli, O Smithies - 1984 - academic.oup.com
Abstract The University of Wisconsin Genetics Computer Group (UWGCG) has been
organized to develop computational tools for the analysis and publication of biological …
organized to develop computational tools for the analysis and publication of biological …
An evolutionary perspective on synonymous codon usage in unicellular organisms
Observed patterns of synonymous codon usage are explained in terms of the joint effects of
mutation, selection, and random drift. Examination of the codon usage in 165 Escherichia …
mutation, selection, and random drift. Examination of the codon usage in 165 Escherichia …
Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes
PM Sharp, TMF Tuohy, KR Mosurski - Nucleic acids research, 1986 - academic.oup.com
Codon usage data has been compiled for 110 yeast genes. Cluster analysis on relative
synonymous codon usage revealed two distinct groups of genes. One group corresponds to …
synonymous codon usage revealed two distinct groups of genes. One group corresponds to …
The selection-mutation-drift theory of synonymous codon usage.
M Bulmer - Genetics, 1991 - academic.oup.com
It is argued that the bias in synonymous codon usage observed in unicellular organisms is
due to a balance between the forces of selection and mutation in a finite population, with …
due to a balance between the forces of selection and mutation in a finite population, with …
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
A Ullrich, L Coussens, JS Hayflick, TJ Dull, A Gray… - Nature, 1984 - nature.com
Abstract The complete 1,210-amino acid sequence of the human epidermal growth factor
(EGF) receptor precursor, deduced from cDNA clones derived from placental and A431 …
(EGF) receptor precursor, deduced from cDNA clones derived from placental and A431 …