Bioactive peptides: From basic research to clinical trials and commercialization

P Duffuler, KS Bhullar… - Journal of agricultural …, 2022 - ACS Publications
Chronic diseases, including metabolic diseases, have become a worldwide public health
issue. Research regarding the use of bioactive peptides or protein hydrolysates derived from …

[HTML][HTML] Antioxidant, antimicrobial and anticarcinogenic activities of bovine milk proteins and their hydrolysates-a review

M Bielecka, G Cichosz, H Czeczot - International Dairy Journal, 2022 - Elsevier
Milk proteins and the products of their hydrolysis are characterised by high levels of
biological activity. The health-promoting potential of bovine milk proteins, peptides and …

[HTML][HTML] Considering food matrix and gastrointestinal effects in enhancing bioactive peptide absorption and bioavailability

X Sun, C Acquah, RE Aluko, CC Udenigwe - Journal of Functional Foods, 2020 - Elsevier
Bioavailability of bioactive peptides (BAPs) represents the amount of peptides absorbed
through normal pathways, after oral intake, and distributed in target tissues to exhibit …

An updated review on food‐derived bioactive peptides: Focus on the regulatory requirements, safety, and bioavailability

PJ Patil, M Usman, C Zhang… - … Reviews in Food …, 2022 - Wiley Online Library
Food‐derived bioactive peptides (BAPs) are recently utilized as functional food raw
materials owing to their potential health benefits. Although there is a huge amount of …

Protein degradation and peptide release from milk proteins in human jejunum. Comparison with in vitro gastrointestinal simulation

J Sanchón, S Fernández-Tomé, B Miralles… - Food chemistry, 2018 - Elsevier
Human jejunal digests after oral ingestion of casein and whey protein were collected by a
nasogastric tube and protein degradation and peptide release was compared with that …

[HTML][HTML] Digestion of milk proteins: Comparing static and dynamic in vitro digestion systems with in vivo data

L Egger, O Ménard, C Baumann, D Duerr… - Food Research …, 2019 - Elsevier
In the frame of the COST action INFOGEST, a static in vitro digestion protocol has been
elaborated aiming at the improvement of data comparability by harmonizing the …

Bioprospecting for bioactive peptide production by lactic acid bacteria isolated from fermented dairy food

D Tagliazucchi, S Martini, L Solieri - Fermentation, 2019 - mdpi.com
With rapidly ageing populations, the world is experiencing unsustainable healthcare from
chronic diseases such as metabolic, cardiovascular, neurodegenerative, and cancer …

Food matrix interaction and bioavailability of bioactive peptides: Two faces of the same coin?

CC Udenigwe, V Fogliano - Journal of Functional Foods, 2017 - Elsevier
Several peptides derived from food protein digestion possess regulatory functions that can
lead to health promotion. Such peptides can be used as nutraceuticals and their inclusion as …

Strategies for the discovery and identification of food protein-derived biologically active peptides

AB Nongonierma, RJ FitzGerald - Trends in Food Science & Technology, 2017 - Elsevier
Background The widespread application of protein-derived bioactive peptides (BAPs) with
health promoting properties in human nutrition is currently limited. This may be due to the …

Identification, production and bioactivity of casein phosphopeptides–A review

M Tenenbaum, B Deracinois, C Dugardin… - Food Research …, 2022 - Elsevier
Milk and dairy products are significant sources of proteins and peptides impacting human
health. In this way, the interest in CPPs, bioactive phosphorylated peptides resulting from the …