Crossing the blood-brain barrier with nanoparticles
The blood-brain barrier (BBB) is one of the most essential protection mechanisms in the
central nervous system (CNS). It selectively allows individual molecules such as small lipid …
central nervous system (CNS). It selectively allows individual molecules such as small lipid …
Targeting the transferrin receptor for brain drug delivery
Obtaining efficient drug delivery to the brain remains the biggest challenge for the
development of therapeutics to treat diseases of the central nervous system. The main …
development of therapeutics to treat diseases of the central nervous system. The main …
Nanoparticles types, classification, characterization, fabrication methods and drug delivery applications
S Bhatia, S Bhatia - Natural polymer drug delivery systems: Nanoparticles …, 2016 - Springer
The most emerging branch in pharmaceutical sciences known as “Pharmaceutical
nanotechnology” presents new tools, opportunities and scope, which are expected to have …
nanotechnology” presents new tools, opportunities and scope, which are expected to have …
Transport of drugs across the blood–brain barrier by nanoparticles
S Wohlfart, S Gelperina, J Kreuter - Journal of controlled release, 2012 - Elsevier
The central nervous system is well protected by the blood–brain barrier (BBB) which
maintains its homeostasis. Due to this barrier many potential drugs for the treatment of …
maintains its homeostasis. Due to this barrier many potential drugs for the treatment of …
Current applications of nanoparticles in infectious diseases
For decades infections have been treated easily with drugs. However, in the 21st century,
they may become lethal again owing to the development of antimicrobial resistance …
they may become lethal again owing to the development of antimicrobial resistance …
[HTML][HTML] Nanomaterials designed for antiviral drug delivery transport across biological barriers
Viral infections are a major global health problem, representing a significant cause of
mortality with an unfavorable continuously amplified socio-economic impact. The increased …
mortality with an unfavorable continuously amplified socio-economic impact. The increased …
Multifunctional and stimuli-responsive nanocarriers for targeted therapeutic delivery
Introduction Nanocarrier-based delivery systems offer multiple benefits to overcome
limitations of the traditional drug dosage forms, such as protection of the drug, enhanced …
limitations of the traditional drug dosage forms, such as protection of the drug, enhanced …
Antiretroviral neurotoxicity
K Robertson, J Liner, RB Meeker - Journal of neurovirology, 2012 - Springer
Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV
burden, however, poor penetration into the central nervous system (CNS) provides …
burden, however, poor penetration into the central nervous system (CNS) provides …
Nano-based approach to combat emerging viral (NIPAH virus) infection
Emergence of new virus and their heterogeneity are growing at an alarming rate. Sudden
outburst of Nipah virus (NiV) has raised serious question about their instant management …
outburst of Nipah virus (NiV) has raised serious question about their instant management …
Getting into the brain: Potential of nanotechnology in the management of NeuroAIDS
In spite of significant advances in antiretroviral (ARV) therapy, the elimination of human
immunodeficiency virus (HIV) reservoirs from the periphery and the central nervous system …
immunodeficiency virus (HIV) reservoirs from the periphery and the central nervous system …