[PDF][PDF] Low back pain: guidelines for the clinical classification of predominant neuropathic, nociceptive, or central sensitization pain

J Nijs, A Apeldoorn, H Hallegraeff, J Clark, R Smeets… - Pain physician, 2015‏ - academia.edu
Background: Low back pain (LBP) is a heterogeneous disorder including patients with
dominant nociceptive (eg, myofascial low back pain), neuropathic (eg, lumbar …

[HTML][HTML] The definition, assessment, and prevalence of (human assumed) central sensitisation in patients with chronic low back pain: a systematic review

I Schuttert, H Timmerman, KK Petersen… - Journal of clinical …, 2021‏ - mdpi.com
Central sensitisation is assumed to be one of the underlying mechanisms for chronic low
back pain. Because central sensitisation is not directly assessable in humans, the term …

Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis

ME McPhee, HB Vaegter, T Graven-Nielsen - Pain, 2020‏ - journals.lww.com
Altered pronociceptive and antinociceptive mechanisms are often implicated in painful
conditions and have been increasingly studied over the past decade. For some painful …

[HTML][HTML] Individual variation in pain sensitivity and conditioned pain modulation in acute low back pain: effect of stimulus type, sleep, and psychological and lifestyle …

DM Klyne, GL Moseley, M Sterling, MF Barbe… - The Journal of …, 2018‏ - Elsevier
Generalized hyperalgesia and impaired pain modulation are reported in chronic low back
pain (LBP). Few studies have tested whether these features are present in the acute phase …

Chronic widespread back pain is distinct from chronic local back pain: evidence from quantitative sensory testing, pain drawings, and psychometrics

A Gerhardt, W Eich, S Janke, S Leisner… - The Clinical journal …, 2016‏ - journals.lww.com
Objectives: Whether chronic localized pain (CLP) and chronic widespread pain (CWP) have
different mechanisms or to what extent they overlap in their pathophysiology is controversial …

[HTML][HTML] Are signs of central sensitization in acute low back pain a precursor to poor outcome?

DM Klyne, GL Moseley, M Sterling, MF Barbe… - The journal of pain, 2019‏ - Elsevier
Central sensitization is considered to have a pathophysiological role in chronic low back
pain (LBP). Whether individuals with increased central sensitization early in their condition …

How does myofascial physical therapy attenuate pain in chronic pelvic pain syndrome?

K Grinberg, I Weissman-Fogel… - Pain Research and …, 2019‏ - Wiley Online Library
Background. Chronic pelvic pain syndrome (CPPS) is a multifactorial disorder comprising
structural and functional muscular abnormalities, a dysfunctional pain system, and …

Neuropathic pain and Kv7 voltage-gated potassium channels: the potential role of Kv7 activators in the treatment of neuropathic pain

A Abd-Elsayed, M Jackson, SL Gu, K Fiala… - Molecular …, 2019‏ - journals.sagepub.com
Neuropathic pain conditions severely and chronically affect the quality of life in a large
human population, but the pain conditions are not adequately managed due to poor …

Relative contributions of the nervous system, spinal tissue and psychosocial health to non‐specific low back pain: Multivariate meta‐analysis

SD Tagliaferri, SK Ng, BM Fitzgibbon… - … Journal of Pain, 2022‏ - Wiley Online Library
Abstract Background and Objectives Nervous system, psychosocial and spinal tissue
biomarkers are associated with non‐specific low back pain (nsLBP), though relative …

Subjects with knee osteoarthritis exhibit widespread hyperalgesia to pressure and cold

P Moss, E Knight, A Wright - PloS one, 2016‏ - journals.plos.org
Hyperalgesia to mechanical and thermal stimuli are characteristics of a range of disorders
such as tennis elbow, whiplash and fibromyalgia. This study evaluated the presence of local …