Carbohydrate-active enzymes (CAZymes) in the gut microbiome

JF Wardman, RK Bains, P Rahfeld… - Nature Reviews …, 2022 - nature.com
The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …

Ultra-processed foods and human health: from epidemiological evidence to mechanistic insights

B Srour, MC Kordahi, E Bonazzi… - The lancet …, 2022 - thelancet.com
Epidemiological studies have suggested a role for ultra-processed foods in numerous
chronic inflammatory diseases such as inflammatory bowel diseases and metabolic …

Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota

AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

V Maini Rekdal, EN Bess, JE Bisanz, PJ Turnbaugh… - Science, 2019 - science.org
INTRODUCTION Parkinson's disease is a debilitating neurological condition affecting more
than 1% of the global population aged 60 and above. The primary medication used to treat …

Clostridium species as probiotics: potentials and challenges

P Guo, K Zhang, X Ma, P He - Journal of animal science and …, 2020 - Springer
Clostridium species, as a predominant cluster of commensal bacteria in our gut, exert lots of
salutary effects on our intestinal homeostasis. Up to now, Clostridium species have been …

Gut microbiota and colonization resistance against bacterial enteric infection

QR Ducarmon, RD Zwittink, BVH Hornung… - Microbiology and …, 2019 - Am Soc Microbiol
The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

The Western diet–microbiome-host interaction and its role in metabolic disease

MK Zinöcker, IA Lindseth - Nutrients, 2018 - mdpi.com
The dietary pattern that characterizes the Western diet is strongly associated with obesity
and related metabolic diseases, but biological mechanisms supporting these associations …

The ancestral and industrialized gut microbiota and implications for human health

ED Sonnenburg, JL Sonnenburg - Nature Reviews Microbiology, 2019 - nature.com
Human-associated microbial communities have adapted to environmental pressures. Doses
of antibiotics select for a community with increased antibiotic resistance, inflammation is …

The social network of microorganisms—how auxotrophies shape complex communities

K Zengler, LS Zaramela - Nature Reviews Microbiology, 2018 - nature.com
Microorganisms engage in complex interactions with other organisms and their
environment. Recent studies have shown that these interactions are not limited to the …

Simple animal models for microbiome research

AE Douglas - Nature Reviews Microbiology, 2019 - nature.com
The health and fitness of animals, including humans, are influenced by the presence and
composition of resident microbial communities. The development of rational microbial …