Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
Balanced immune regulation is crucial for recognizing an invading pathogen, its killing, and
elimination. Toll‐like receptors (TLRs) are the key regulators of the innate immune system. It …

[HTML][HTML] Inflammation in COVID-19: from pathogenesis to treatment

RSY Wong - International journal of clinical and experimental …, 2021 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) was declared a pandemic in March
2020 by the World Health Organization (WHO). To date, there were> 163 million confirmed …

Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

[HTML][HTML] COVID-19 a triggering factor of autoimmune and multi-inflammatory diseases

EK Sher, A Ćosović, A Džidić-Krivić, EK Farhat, E Pinjić… - Life sciences, 2023 - Elsevier
SARS-Cov-2 virus has attracted a lot of attention globally, due to the autoimmune and
inflammatory processes that were observed during the development of Covid-19 disease …

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein

J Gasparello, E D'Aversa, C Papi, L Gambari, B Grigolo… - Phytomedicine, 2021 - Elsevier
Background A key clinical feature of COVID-19 is a deep inflammatory state known as
“cytokine storm” and characterized by high expression of several cytokines, chemokines and …

The Use of CytoSorb Therapy in Critically Ill COVID‐19 Patients: Review of the Rationale and Current Clinical Experiences

JC Ruiz-Rodríguez, Z Molnar… - … Care Research and …, 2021 - Wiley Online Library
The COVID‐19 pandemic has led to the biggest global health crisis of our lifetime. There is
accumulating evidence that a substantial number of critically ill COVID‐19 patients exhibit a …

Vagus nerve stimulation: a potential adjunct therapy for COVID-19

E Azabou, G Bao, R Bounab, N Heming… - Frontiers in …, 2021 - frontiersin.org
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
coronavirus disease 2019 (COVID-19) through excessive end organ inflammation. Despite …

Can selenium reduce the susceptibility and severity of SARS-CoV-2?—A comprehensive review

M Majeed, K Nagabhushanam, P Prakasan… - International journal of …, 2022 - mdpi.com
The SARS-CoV-2 infection is a highly contagious viral infection, which has claimed millions
of lives in the last two years. The infection can cause acute respiratory distress, myocarditis …