S-adenosylmethionine in Liver Health, Injury, and Cancer
SC Lu, JM Mato - Physiological reviews, 2012 - journals.physiology.org
S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological
methyl donor synthesized in all mammalian cells but most abundantly in the liver …
methyl donor synthesized in all mammalian cells but most abundantly in the liver …
Toxicogenomic approaches for understanding molecular mechanisms of heavy metal mutagenicity and carcinogenicity
P Koedrith, HL Kim, JI Weon, YR Seo - International journal of hygiene and …, 2013 - Elsevier
Heavy metals that are harmful to humans include arsenic, cadmium, chromium, lead,
mercury, and nickel. Some metals or their related compounds may even cause cancer …
mercury, and nickel. Some metals or their related compounds may even cause cancer …
High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues
Metabolic profiling, metabolomic and metabonomic studies require robust study protocols for
any large-scale comparisons and evaluations. Detailed methods for solution-state NMR …
any large-scale comparisons and evaluations. Detailed methods for solution-state NMR …
Urinary metabolic phenoty** differentiates children with autism from their unaffected siblings and age-matched controls
Autism is an early onset developmental disorder with a severe life-long impact on behavior
and social functioning that has associated metabolic abnormalities. The urinary metabolic …
and social functioning that has associated metabolic abnormalities. The urinary metabolic …
Systems responses of rats to aflatoxin B1 exposure revealed with metabonomic changes in multiple biological matrices
L Zhang, Y Ye, Y An, Y Tian, Y Wang… - Journal of proteome …, 2011 - ACS Publications
Exposure to aflatoxins causes liver fibrosis and hepatocellular carcinoma posing a
significant health risk for human populations and livestock. To understand the mammalian …
significant health risk for human populations and livestock. To understand the mammalian …
Metabolomics reveals that aryl hydrocarbon receptor activation by environmental chemicals induces systemic metabolic dysfunction in mice
Environmental exposure to dioxins and dioxin-like compounds poses a significant health
risk for human health. Develo** a better understanding of the mechanisms of toxicity …
risk for human health. Develo** a better understanding of the mechanisms of toxicity …
Perturbation of bile acid homeostasis is an early pathogenesis event of drug induced liver injury in rats
M Yamazaki, M Miyake, H Sato, N Masutomi… - Toxicology and applied …, 2013 - Elsevier
Drug-induced liver injury (DILI) is a significant consideration for drug development. Current
preclinical DILI assessment relying on histopathology and clinical chemistry has limitations …
preclinical DILI assessment relying on histopathology and clinical chemistry has limitations …
High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies
High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …
Hepatic toxicity biomarkers
X Yang, LK Schnackenberg, Q Shi… - Biomarkers in toxicology, 2014 - Elsevier
The liver is the largest internal organ in the human body and it is the main site for the
metabolism of endogenous molecules and xenobiotics. Drug-induced liver injury is one of …
metabolism of endogenous molecules and xenobiotics. Drug-induced liver injury is one of …
NMR-based multi parametric quality control of fruit juices: SGF profiling
M Spraul, B Schütz, P Rinke, S Koswig, E Humpfer… - Nutrients, 2009 - mdpi.com
With SGF Profiling™ we introduce an NMR-based screening method for the quality control of
fruit juices. This method has been developed in a joint effort by Bruker BioSpin GmbH and …
fruit juices. This method has been developed in a joint effort by Bruker BioSpin GmbH and …