Biocatalysts that are eco-friendly, sustainable, and highly specific have great potential for
applications in the production of fine chemicals, food, detergents, biofuels, pharmaceuticals …

Biocatalysis is currently undergoing a profound transformation. The field moves from relying
on nature's chemical logic to a discipline that exploits generic activation modes, allowing for …

Engineered hemoproteins can selectively incorporate nitrogen from nitrene precursors like
hydroxylamine, O-substituted hydroxylamines, and organic azides into organic molecules …

Enantioselective C–H amidation offers attractive means to assemble C–N bonds to
synthesize high-added value, nitrogen-containing molecules. In recent decades …

Photochemical deracemization has emerged as one of the most straightforward approaches
to access highly enantioenriched compounds in recent years. While excited-state events …

Lactones are cyclic esters with extensive applications in materials science, medicinal
chemistry, and the food and perfume industries. Nature's strategy for the synthesis of many …

Exploring the promiscuity of native enzymes presents a promising strategy for expanding
their synthetic applications, particularly for catalyzing challenging reactions in non-native …

Herein, multiple types of chiral Os (II) complexes have been designed to address the
appealing yet challenging asymmetric C (sp3)− H functionalization, among which the Os …

Nitrene transfer reactions catalyzed by heme proteins have broad potential for the
stereoselective formation of carbon–nitrogen bonds. However, competition between …

Amine structures are widely present in various biologically active natural products, drug
molecules, and material structures. Among the various strategies of amine synthesis, C (sp3) …