Wilms' tumour 1 (WT1) in development, homeostasis and disease

ND Hastie - Development, 2017‏ - journals.biologists.com
The study of genes mutated in human disease often leads to new insights into biology as
well as disease mechanisms. One such gene is Wilms' tumour 1 (WT1), which plays multiple …

Aniridia. A review

LB Nelson, GL Spaeth, TS Nowinski, CE Margo… - Survey of …, 1984‏ - Elsevier
Aniridia occurs as a phenotypically heterogeneous condition which may be inherited as an
autosomal dominant disorder or as part of several systemic syndromes. It has been linked …

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

D Malkin, FP Li, LC Strong, JF Fraumeni Jr, CE Nelson… - Science, 1990‏ - science.org
Familial cancer syndromes have helped to define the role of tumor suppressor genes in the
development of cancer. The dominantly inherited Li-Fraumeni syndrome (LFS) is of …

[فهرست منابع][C] DeVita, Hellman, and Rosenberg's cancer: principles & practice of oncology

VT DeVita - 2008‏ - books.google.com
Acclaimed by the worldwide medical community as" a staple reference text in the medical
oncologist's library"(JAMA), DeVita, Hellman, and Rosenberg's Cancer: Principles and …

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

KM Call, T Glaser, CY Ito, AJ Buckler, J Pelletier… - Cell, 1990‏ - cell.com
We have isolated a series of genomic and cDNA clones map** within the boundaries of
constitutional and tumor deletions that define the Wilms' tumor locus on human chromsome …

[HTML][HTML] A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

JA Trofatter, MM MacCollin, JL Rutter, JR Murrell… - Cell, 1993‏ - cell.com
Abstract Neurofibromatosis 2 (NF2) is a dominantly inherited disorder characterized by the
occurrence of bilateral vestibular schwannomas and other central nervous system tumors …

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

J Pelletier, W Bruening, CE Kashtan, SM Mauer… - Cell, 1991‏ - Elsevier
Denys-Drash syndrome is a rare human condition inwhich severe urogenital aberrations
result in renal fail ure, pseudohermaphroditism, and Wilms' tumor (neph roblastoma). To …

[کتاب][B] Cancer cytogenetics: chromosomal and molecular genetic aberrations of tumor cells

S Heim, F Mitelman - 2015‏ - books.google.com
The first three editions of this acclaimed book presented a much-needed conceptual
synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a …

Positional cloning and characterization of a paired box-and homeobox-containing gene from the aniridia region

CCT Ton, H Hirvonen, H Miwa, MM Weil, P Monaghan… - Cell, 1991‏ - cell.com
Based on the map location of the aniridia (AN) locus in human chromosomal band 11~ 13,
we have cloned a candidate AN cDNA (Dl lS812E) that Is completely or partially deleted in …

The candidate Wilms' tumour gene is involved in genitourinary development

K Pritchard-Jones, S Fleming, D Davidson, W Bickmore… - Nature, 1990‏ - nature.com
WILMS'tumour is an embryonic kidney tumour thought to arise through aberrant
mesenchymal stem cell differentiation1 and to result from loss of function of a'tumour …