Fatty acids derivatives from eukaryotic microalgae, pathways and potential applications

M Blasio, S Balzano - Frontiers in Microbiology, 2021 - frontiersin.org
The exploitation of petrochemical hydrocarbons is compromising ecosystem and human
health and biotechnological research is increasingly focusing on sustainable materials from …

The evolution and diversity of actin-dependent cell migration

LK Fritz-Laylin, MA Titus - Molecular biology of the cell, 2023 - molbiolcell.org
Many eukaryotic cells, including animal cells and unicellular amoebae, use dynamic-actin
networks to crawl across solid surfaces. Recent discoveries of actin-dependent crawling in …

Microbial predators form a new supergroup of eukaryotes

DV Tikhonenkov, KV Mikhailov, RMR Gawryluk… - Nature, 2022 - nature.com
Molecular phylogenetics of microbial eukaryotes has reshaped the tree of life by
establishing broad taxonomic divisions, termed supergroups, that supersede the traditional …

Repeated co-option of HMG-box genes for sex determination in brown algae and animals

R Luthringer, M Raphalen, C Guerra, S Colin… - Science, 2024 - science.org
In many eukaryotes, genetic sex determination is not governed by XX/XY or ZW/ZZ systems
but by a specialized region on the poorly studied U (female) or V (male) sex chromosomes …

Phylogenomic insights into the early diversification of fungi

JFH Strassert, MT Monaghan - Current Biology, 2022 - cell.com
Phylogenomic analyses have boosted our understanding of the evolutionary trajectories of
all living forms by providing continuous improvements to the tree of life. 1, 2, 3, 4, 5 Within …

RNA-guided RNA silencing by an Asgard archaeal Argonaute

C Bastiaanssen, P Bobadilla Ugarte, K Kim… - Nature …, 2024 - nature.com
Argonaute proteins are the central effectors of RNA-guided RNA silencing pathways in
eukaryotes, playing crucial roles in gene repression and defense against viruses and …

Accurate and sensitive detection of microbial eukaryotes from whole metagenome shotgun sequencing

AL Lind, KS Pollard - Microbiome, 2021 - Springer
Background Microbial eukaryotes are found alongside bacteria and archaea in natural
microbial systems, including host-associated microbiomes. While microbial eukaryotes are …

Eukaryotic CD-NTase, STING, and viperin proteins evolved via domain shuffling, horizontal transfer, and ancient inheritance from prokaryotes

EM Culbertson, TC Levin - PLoS Biology, 2023 - journals.plos.org
Animals use a variety of cell-autonomous innate immune proteins to detect viral infections
and prevent replication. Recent studies have discovered that a subset of mammalian …

Functional and evolutionary significance of unknown genes from uncultivated taxa

Á Rodríguez del Río, J Giner-Lamia, CP Cantalapiedra… - Nature, 2024 - nature.com
Many of the Earth's microbes remain uncultured and understudied, limiting our
understanding of the functional and evolutionary aspects of their genetic material, which …

Sequence similarity networks bear out hierarchical relationships of green cytochrome P450

A Dhabalia Ashok, JN Freitag, I Irisarri… - Physiologia …, 2024 - Wiley Online Library
Land plants have diversified enzyme families. One of the most prominent is the cytochrome
P450 (CYP or CYP450) family. With over 443,000 CYP proteins sequenced across the tree …