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Neural dedifferentiation in the aging brain
JD Koen, MD Rugg - Trends in cognitive sciences, 2019 - cell.com
Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …
Neurocognitive aging and the hippocampus across species
There is extensive evidence that aging is associated with impairments in episodic memory.
Many of these changes have been ascribed to neurobiological alterations to the …
Many of these changes have been ascribed to neurobiological alterations to the …
Increased prefrontal activity with aging reflects nonspecific neural responses rather than compensation
Elevated prefrontal cortex activity is often observed in healthy older adults despite declines
in their memory and other cognitive functions. According to one view, this activity reflects a …
in their memory and other cognitive functions. According to one view, this activity reflects a …
Healthy ageing reduces the precision of episodic memory retrieval.
SM Korkki, FR Richter, P Jeyarathnarajah… - Psychology and …, 2020 - psycnet.apa.org
Episodic memory declines with older age, but it is unresolved whether this decline reflects
reduced probability of successfully retrieving information from memory, or decreased …
reduced probability of successfully retrieving information from memory, or decreased …
Physical activity improves cognition: possible explanations
B Koščak Tivadar - Biogerontology, 2017 - Springer
Good cognitive abilities (CA) enable autonomy, improve social inclusion and act
preventively. Regular physical activity (PA) reduces the risk of develo** Alzheimer's …
preventively. Regular physical activity (PA) reduces the risk of develo** Alzheimer's …
Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults
Age-related episodic memory decline is characterized by striking heterogeneity across
individuals. Hippocampal pattern completion is a fundamental process supporting episodic …
individuals. Hippocampal pattern completion is a fundamental process supporting episodic …
Reduced fidelity of neural representation underlies episodic memory decline in normal aging
Emerging studies have emphasized the importance of the fidelity of cortical representation in
forming enduring episodic memory. No study, however, has examined whether there are …
forming enduring episodic memory. No study, however, has examined whether there are …
GABA levels in ventral visual cortex decline with age and are associated with neural distinctiveness
Age-related neural dedifferentiation—a decline in the distinctiveness of neural
representations in the aging brain—has been associated with age-related declines in …
representations in the aging brain—has been associated with age-related declines in …
[HTML][HTML] Neural evidence for age-related differences in representational quality and strategic retrieval processes
Mounting behavioral evidence suggests that declines in both representational quality and
controlled retrieval processes contribute to episodic memory decline with age. The present …
controlled retrieval processes contribute to episodic memory decline with age. The present …
Contributions of representational distinctiveness and stability to memory performance and age differences
Long-standing theories of cognitive aging suggest that memory decline is associated with
age-related differences in the way information is neurally represented. Multivariate pattern …
age-related differences in the way information is neurally represented. Multivariate pattern …