Rheumatoid arthritis (RA) is an autoimmune disease that commonly causes inflammation
and bone destruction in multiple joints. Inflammatory cytokines, such as IL-6 and TNF-α, play …

Neutrophils are first responders of the immune system, rapidly migrating into affected tissues
in response to injury or infection. To effectively call in this first line of defense, strategically …

Hashimoto's thyroiditis (HT) is the most common autoimmune disease characterized by
lymphocytic infiltration and thyrocyte destruction. Dissection of the interaction between the …

The Duffy antigen receptor for chemokines (DARC) belongs to a family of'silent'heptahelical
chemokine receptors that do not couple to G proteins and fail to transmit measurable …

Neutrophils are essential components of the immune system and have vital roles in the
pathogenesis of autoimmune disorders. As effector cells, neutrophils promote autoimmune …

Background and purpose: Chemokines orchestrate neutrophil recruitment to inflammatory
foci. In the present study, we evaluated the participation of three chemokines, KC/CXCL1 …

Chemokines are pivotal players in instigation and perpetuation of synovitis through
leukocytes egress from the blood circulation into the inflamed articulation. Multitudinous …

Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get
new issue alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle …

Significant advances have been made in the last 5 years that have finally allowed
investigators to start targeting stromal cells such as fibroblasts in inflammatory disease …

Chemokines, a family of small secreted chemotactic cytokines, and their G protein-coupled
seven transmembrane spanning receptors control the migratory patterns, positioning and …