Four main histological subtypes of ovarian cancer exist: serous (the most frequent),
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …

The mechanisms regulating exhaustion of tumor-infiltrating lymphocytes (TIL) and
responsiveness to PD-1 blockade remain partly unknown. In human ovarian cancer, we …

Epithelial ovarian cancer represents the most lethal gynecological malignancy in the
developed world, and can be divided into five main histological subtypes: high grade …

Restoration of anti-tumor immunity by blocking PD-L1 signaling through the use of
antibodies has proven to be beneficial in cancer therapy. Here, we show that BET …

The validation of prognostic biomarkers in large independent patient cohorts is a major
bottleneck in ovarian cancer research. We implemented an online tool to assess the …

Background Ovarian cancer (OV) is the most lethal gynecological cancer in women. We aim
to develop a generalized, individualized immune prognostic signature that can stratify and …

Polycomb group proteins (PCGs) are involved in repression of genes that are required for
stem cell differentiation. Recently, it was shown that promoters of PCG target genes (PCGTs) …

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Intense
efforts have been made to elucidate the pathogeny, but the molecular mechanisms of HCC …

Motivation: Gene expression profiling has shown great potential in outcome prediction for
different types of cancers. Nevertheless, small sample size remains a bottleneck in obtaining …

The Yes‐associated protein (YAP)/Hippo pathway has been implicated in tissue
development, regeneration, and tumorigenesis. However, its role in cholangiocarcinoma …