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Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
Abstract Purpose This Position Paper aims to review and discuss the available data on
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
Clinical practice guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing: a consensus review by the Japanese …
K Matsumoto, K Oda, K Shoji, Y Hanai, Y Takahashi… - Pharmaceutics, 2022 - mdpi.com
Background: To promote model-informed precision dosing (MIPD) for vancomycin (VCM),
we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical …
we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical …
Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American …
Methods These are the consensus statements and guideline of ASHP, IDSA, the Pediatric
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …
[HTML][HTML] The effect of pathophysiology on pharmacokinetics in the critically ill patient—concepts appraised by the example of antimicrobial agents
Critically ill patients are at high risk for development of life-threatening infection leading to
sepsis and multiple organ failure. Adequate antimicrobial therapy is pivotal for optimizing the …
sepsis and multiple organ failure. Adequate antimicrobial therapy is pivotal for optimizing the …
A quasi-experiment to study the impact of vancomycin area under the concentration-time curve-guided dosing on vancomycin-associated nephrotoxicity
NA Finch, EJ Zasowski, KP Murray… - Antimicrobial agents …, 2017 - journals.asm.org
Evidence suggests that maintenance of vancomycin trough concentrations at between 15
and 20 mg/liter, as currently recommended, is frequently unnecessary to achieve the daily …
and 20 mg/liter, as currently recommended, is frequently unnecessary to achieve the daily …
Are vancomycin trough concentrations adequate for optimal dosing?
MN Neely, G Youn, B Jones, RW Jelliffe… - Antimicrobial agents …, 2014 - journals.asm.org
The current vancomycin therapeutic guidelines recommend the use of only trough
concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both …
concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both …
[HTML][HTML] Innovative approaches to optimizing the delivery of vancomycin in individual patients
The delivery of personalized antimicrobial therapy is a critical component in the treatment of
patients with invasive infections. Vancomycin, the drug of choice for infections due to …
patients with invasive infections. Vancomycin, the drug of choice for infections due to …
The emperor's new clothes: prospective observational evaluation of the association between initial vancomycin exposure and failure rates among adult hospitalized …
TP Lodise Jr, SL Rosenkranz… - Clinical infectious …, 2020 - academic.oup.com
Background Vancomycin is the most commonly administered antibiotic in hospitalized
patients, but optimal exposure targets remain controversial. To clarify the therapeutic …
patients, but optimal exposure targets remain controversial. To clarify the therapeutic …
Vancomycin revisited–60 years later
E Rubinstein, Y Keynan - Frontiers in public health, 2014 - frontiersin.org
Vancomycin is one of the older antibiotics that has been now in clinical use close to 60
years. Earlier on, vancomycin was associated with many side effects including vestibular …
years. Earlier on, vancomycin was associated with many side effects including vestibular …
Pharmacokinetic and pharmacodynamic principles of anti-infective dosing
NJ Onufrak, A Forrest, D Gonzalez - Clinical therapeutics, 2016 - Elsevier
Purpose An understanding of the pharmacokinetic (PK) and pharmacodynamic (PD)
principles that determine response to antimicrobial therapy can provide the clinician with …
principles that determine response to antimicrobial therapy can provide the clinician with …