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Liposome and immune system interplay: Challenges and potentials
Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …
Analyzing the surface of functional nanomaterials—how to quantify the total and derivatizable number of functional groups and ligands
D Geißler, N Nirmalananthan-Budau, L Scholtz… - Microchimica Acta, 2021 - Springer
Functional nanomaterials (NM) of different size, shape, chemical composition, and surface
chemistry are of increasing relevance for many key technologies of the twenty-first century …
chemistry are of increasing relevance for many key technologies of the twenty-first century …
Glycopolymeric Nanoparticles Enrich Less Immunogenic Protein Coronas, Reduce Mononuclear Phagocyte Clearance, and Improve Tumor Delivery Compared to …
Nanoparticles (NPs) offer significant promise as drug delivery vehicles; however, their in
vivo efficacy is often hindered by the formation of a protein corona (PC), which influences …
vivo efficacy is often hindered by the formation of a protein corona (PC), which influences …
Quantification of surface functional groups on silica nanoparticles: Comparison of thermogravimetric analysis and quantitative NMR
Thermogravimetric analysis (TGA) coupled with evolved gas analysis-FT-IR has been
examined as a potential method to study the functional group content for surface modified …
examined as a potential method to study the functional group content for surface modified …
[HTML][HTML] Ultrasound improves the delivery and therapeutic effect of nanoparticle-stabilized microbubbles in breast cancer xenografts
Compared with conventional chemotherapy, encapsulation of drugs in nanoparticles can
improve efficacy and reduce toxicity. However, delivery of nanoparticles is often insufficient …
improve efficacy and reduce toxicity. However, delivery of nanoparticles is often insufficient …
Sonoporation using nanoparticle-loaded microbubbles increases cellular uptake of nanoparticles compared to co-incubation of nanoparticles and microbubbles
S Snipstad, S Hanstad, A Bjørkøy, Ý Mørch… - Pharmaceutics, 2021 - mdpi.com
Therapeutic agents can benefit from encapsulation in nanoparticles, due to improved
pharmacokinetics and biodistribution, protection from degradation, increased cellular uptake …
pharmacokinetics and biodistribution, protection from degradation, increased cellular uptake …
[HTML][HTML] Sonopermeation enhances uptake and therapeutic effect of free and encapsulated cabazitaxel
Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and,
thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to …
thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to …
Cytotoxicity of poly (alkyl cyanoacrylate) nanoparticles
E Sulheim, TG Iversen, V To Nakstad… - International journal of …, 2017 - mdpi.com
Although nanotoxicology has become a large research field, assessment of cytotoxicity is
often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and …
often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and …
Disulfiram-loaded mixed nanoparticles with high drug-loading and plasma stability by reducing the core crystallinity for intravenous delivery
X Zhuo, T Lei, L Miao, W Chu, X Li, L Luo, J Gou… - Journal of Colloid and …, 2018 - Elsevier
To develop an injectable formulation and improve the stability of disulfiram (DSF), DSF was
encapsulated into mixed nanoparticles (DSF-NPs) through a high-pressure homogenization …
encapsulated into mixed nanoparticles (DSF-NPs) through a high-pressure homogenization …
A journey through the emergence of nanomedicines with poly (alkylcyanoacrylate) based nanoparticles
C Vauthier - Journal of Drug Targeting, 2019 - Taylor & Francis
Starting in the late 1970s, the pioneering work of Patrick Couvreur gave birth to the first
biodegradable nanoparticles composed of a biodegradable synthetic polymer. These …
biodegradable nanoparticles composed of a biodegradable synthetic polymer. These …