Liposome and immune system interplay: Challenges and potentials

F Zahednezhad, M Saadat, H Valizadeh… - Journal of Controlled …, 2019 - Elsevier
Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …

Analyzing the surface of functional nanomaterials—how to quantify the total and derivatizable number of functional groups and ligands

D Geißler, N Nirmalananthan-Budau, L Scholtz… - Microchimica Acta, 2021 - Springer
Functional nanomaterials (NM) of different size, shape, chemical composition, and surface
chemistry are of increasing relevance for many key technologies of the twenty-first century …

Glycopolymeric Nanoparticles Enrich Less Immunogenic Protein Coronas, Reduce Mononuclear Phagocyte Clearance, and Improve Tumor Delivery Compared to …

K Hulugalla, O Shofolawe-Bakare, VB Toragall… - ACS …, 2024 - ACS Publications
Nanoparticles (NPs) offer significant promise as drug delivery vehicles; however, their in
vivo efficacy is often hindered by the formation of a protein corona (PC), which influences …

Quantification of surface functional groups on silica nanoparticles: Comparison of thermogravimetric analysis and quantitative NMR

F Kunc, V Balhara, Y Sun, M Daroszewska, ZJ Jakubek… - Analyst, 2019 - pubs.rsc.org
Thermogravimetric analysis (TGA) coupled with evolved gas analysis-FT-IR has been
examined as a potential method to study the functional group content for surface modified …

[HTML][HTML] Ultrasound improves the delivery and therapeutic effect of nanoparticle-stabilized microbubbles in breast cancer xenografts

S Snipstad, S Berg, Ý Mørch, A Bjørkøy… - Ultrasound in medicine …, 2017 - Elsevier
Compared with conventional chemotherapy, encapsulation of drugs in nanoparticles can
improve efficacy and reduce toxicity. However, delivery of nanoparticles is often insufficient …

Sonoporation using nanoparticle-loaded microbubbles increases cellular uptake of nanoparticles compared to co-incubation of nanoparticles and microbubbles

S Snipstad, S Hanstad, A Bjørkøy, Ý Mørch… - Pharmaceutics, 2021 - mdpi.com
Therapeutic agents can benefit from encapsulation in nanoparticles, due to improved
pharmacokinetics and biodistribution, protection from degradation, increased cellular uptake …

[HTML][HTML] Sonopermeation enhances uptake and therapeutic effect of free and encapsulated cabazitaxel

S Snipstad, Ý Mørch, E Sulheim, A Åslund… - Ultrasound in Medicine …, 2021 - Elsevier
Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and,
thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to …

Cytotoxicity of poly (alkyl cyanoacrylate) nanoparticles

E Sulheim, TG Iversen, V To Nakstad… - International journal of …, 2017 - mdpi.com
Although nanotoxicology has become a large research field, assessment of cytotoxicity is
often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and …

Disulfiram-loaded mixed nanoparticles with high drug-loading and plasma stability by reducing the core crystallinity for intravenous delivery

X Zhuo, T Lei, L Miao, W Chu, X Li, L Luo, J Gou… - Journal of Colloid and …, 2018 - Elsevier
To develop an injectable formulation and improve the stability of disulfiram (DSF), DSF was
encapsulated into mixed nanoparticles (DSF-NPs) through a high-pressure homogenization …

A journey through the emergence of nanomedicines with poly (alkylcyanoacrylate) based nanoparticles

C Vauthier - Journal of Drug Targeting, 2019 - Taylor & Francis
Starting in the late 1970s, the pioneering work of Patrick Couvreur gave birth to the first
biodegradable nanoparticles composed of a biodegradable synthetic polymer. These …