The c statistic, or area under the receiver operating characteristic (ROC) curve, achieved
popularity in diagnostic testing, in which the test characteristics of sensitivity and specificity …

Myocardial dysfunction is one of the main predictors of poor outcome in septic patients, with
mortality rates next to 70%. During the sepsis-induced myocardial dysfunction, both …

The recommendations listed in this CPG are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2012, and other selected …

Background Few investigations have evaluated the incremental usefulness of multiple
biomarkers from distinct biologic pathways for predicting the risk of cardiovascular events …

Context Prior studies have demonstrated conflicting results regarding how much information
novel biomarkers add to cardiovascular risk assessment. Objective To evaluate the utility of …

Measurement of biomarkers has revolutionized the work-up of patients with suspected
cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are …

Background—Measurement of B-type natriuretic peptide (BNP) concentration or its
precursor (N-terminal fragment [NT-proBNP]) is recommended in patients with symptoms of …

The use of biomarkers to augment traditional cardiovas-cular risk prediction has attracted
considerable attention in the past decade. This interest has been fueled by the realization …

Background—Cardiovascular risk estimation by novel biomarkers needs assessment in
disease-free population cohorts, followed up for incident cardiovascular events, assaying …

Objectives To enable risk stratification of patients with various types of arterial disease by the
development and validation of models for prediction of recurrent vascular event risk based …