Progressive multiple sclerosis poses a considerable challenge in the evaluation of disease
progression and treatment response owing to its multifaceted pathophysiology. Traditional …

This study explores the use of optical coherence tomography (OCT) to monitor and diagnose
multiple sclerosis (MS). The analysis of reduced total macular volume and peripapillary …

Retinal optical coherence tomography has been identified as biomarker for disease
progression in relapsing-remitting multiple sclerosis (RRMS), while the dynamics of retinal …

While neurodegeneration underlies the pathological basis for permanent disability in
multiple sclerosis (MS), predictive biomarkers for progression are lacking. Using an animal …

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are
autoimmune central nervous system conditions with increasing incidence and prevalence …

Understanding the mechanisms underlying progression and develo** new treatments for
progressive multiple sclerosis (PMS) are among the major challenges in the field of central …

Purpose Retinal layer thickness parameters measured by optical coherence tomography
(OCT) are emerging biomarkers of neuroaxonal degeneration and inflammation in multiple …

Optical coherence tomography (OCT) is gaining increasing relevance in the assessment of
patients with multiple sclerosis. Converging evidence point to the view that neuro-retinal …

This manuscript reviews the primary and secondary endpoints of pivotal phase III trials with
immunomodulatory drugs in multiple sclerosis (MS). Considering the limitations of previous …

Spectral domain‐optical coherence tomography plays a crucial role in the early detection
and monitoring of multiple sclerosis (MS) pathophysiology. We aimed to quantify differences …