Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

[HTML][HTML] Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - Elsevier
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Multisensory gamma stimulation promotes glymphatic clearance of amyloid

MH Murdock, CY Yang, N Sun, PC Pao… - Nature, 2024 - nature.com
The glymphatic movement of fluid through the brain removes metabolic waste,,–.
Noninvasive 40 Hz stimulation promotes 40 Hz neural activity in multiple brain regions and …

Spontaneous behaviour is structured by reinforcement without explicit reward

JE Markowitz, WF Gillis, M Jay, J Wood, RW Harris… - Nature, 2023 - nature.com
Spontaneous animal behaviour is built from action modules that are concatenated by the
brain into sequences,. However, the neural mechanisms that guide the composition of …

A tissue-like neurotransmitter sensor for the brain and gut

J Li, Y Liu, L Yuan, B Zhang, ES Bishop, K Wang… - Nature, 2022 - nature.com
Neurotransmitters play essential roles in regulating neural circuit dynamics both in the
central nervous system as well as at the peripheral, including the gastrointestinal tract …

Mesolimbic dopamine release conveys causal associations

H Jeong, A Taylor, JR Floeder, M Lohmann, S Mihalas… - Science, 2022 - science.org
Learning to predict rewards based on environmental cues is essential for survival. It is
believed that animals learn to predict rewards by updating predictions whenever the …

Disruption of mitochondrial complex I induces progressive parkinsonism

P González-Rodríguez, E Zampese, KA Stout… - Nature, 2021 - nature.com
Loss of functional mitochondrial complex I (MCI) in the dopaminergic neurons of the
substantia nigra is a hallmark of Parkinson's disease. Yet, whether this change contributes to …

Impaired dopamine release in Parkinson's disease

KML Cramb, D Beccano-Kelly, SJ Cragg… - Brain, 2023 - academic.oup.com
Parkinson's disease is the second most common neurodegenerative disease and yet the
early pathophysiological events of the condition and sequences of dysfunction remain …

Improved green and red GRAB sensors for monitoring dopaminergic activity in vivo

Y Zhuo, B Luo, X Yi, H Dong, X Miao, J Wan… - Nature …, 2024 - nature.com
Dopamine (DA) plays multiple roles in a wide range of physiological and pathological
processes via a large network of dopaminergic projections. To dissect the spatiotemporal …

[HTML][HTML] Dopamine and glutamate regulate striatal acetylcholine in decision-making

L Chantranupong, CC Beron, JA Zimmer, MJ Wen… - Nature, 2023 - nature.com
Striatal dopamine and acetylcholine are essential for the selection and reinforcement of
motor actions and decision-making. In vitro studies have revealed an intrastriatal circuit in …