A crucial role for working memory in temporary information processing and guidance of
complex behavior has been recognized for many decades. There is emerging consensus …

Mild cognitive changes, including executive dysfunction, are seen in Parkinson's Disease
(PD). Approximately 30% of individuals with PD develop Parkinson's disease dementia …

Exercise interventions in individuals with Parkinson's disease incorporate goal-based motor
skill training to engage cognitive circuitry important in motor learning. With this exercise …

Alpha-synucleinopathy is postulated to be central to both idiopathic rapid eye movement
sleep behaviour disorder (iRBD) and Parkinson's disease (PD). Growing evidence suggests …

Background Synaptic dysfunction and degeneration are central contributors to the
pathogenesis and progression of parkinsonian disorders. Therefore, identification and …

Objective To examine mortality and associated risk factors, including possible effects of mild
cognitive impairment, imaging, and CSF abnormalities, in a community-based population …

Objective To determine whether neurofilament light chain protein in CSF (cNfL), a sensitive
biomarker of neuroaxonal damage, reflects disease severity or can predict survival in …

Previous studies have shown greater atrophy in grey and white matter of various brain
regions in patients with Parkinson's disease with mild cognitive impairment than in those …

Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …

Cognitive impairment is common in PD, even in early stages. The construct of mild cognitive
impairment has been used to identify clinically evident cognitive impairment without …