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Cobalt and ruthenium complexes with pyrimidine based schiff base: Synthesis, characterization, anticancer activities and electrochemotherapy efficiency
In this study, a new Schiff base ligand and its two M (II) complexes [CoCl· L (H 2 O) 2]· 2H 2
O,[RuCl (p-cymene) L] were synthesized. The structural features were confirmed from their …
O,[RuCl (p-cymene) L] were synthesized. The structural features were confirmed from their …
Halting colorectal cancer metastasis via novel dual nanomolar MMP-9/MAO-A quinoxaline-based inhibitors; design, synthesis, and evaluation
Abstract Matrix metalloproteinase-9 (MMP-9) and monoamine oxidase-A (MAO-A) are
central signaling nodes in CRC and promotors of distant metastasis associated with high …
central signaling nodes in CRC and promotors of distant metastasis associated with high …
Synthesis, characterization, antiproliferative of pyrimidine based ligand and its Ni (II) and Pd (II) complexes and effectiveness of electroporation
In the study, a new Schiff base (ligand) was obtained using 4-aminopyrimidine-2 (1 H)-one,
the starting material, and 2, 3, 4-trimethoxy benzaldehyde. Ni (II) and Pd (II) complexes were …
the starting material, and 2, 3, 4-trimethoxy benzaldehyde. Ni (II) and Pd (II) complexes were …
Synthesis, spectroscopic characterization of novel phthalimides derivatives bearing a 1, 2, 3-triazole unit and examination as potential SARS-CoV-2 inhibitors via in …
A Tan - Journal of Molecular Structure, 2022 - Elsevier
In the present study, novel phthalimide derivatives 8 (af) and 9 (af) bearing a 1, 2, 3-triazole
subunit were synthesized via CuAAC reactions and characterized by 1 H, 13 C NMR, HR …
subunit were synthesized via CuAAC reactions and characterized by 1 H, 13 C NMR, HR …
Novel hybrid isoindole‐1,3(2H)‐dione compounds containing a 1H‐tetrazole moiety: Synthesis, biological evaluation, and molecular docking studies
In this study, novel hybrid isoindole‐1, 3 (2H)‐dione compounds (10 and 11) carrying a 1H‐
tetrazole moiety were synthesized, characterized and their inhibitory properties against …
tetrazole moiety were synthesized, characterized and their inhibitory properties against …
Substituent effects in the formation of a few acenaphthenone-2-ylidene ketones and their molecular docking studies and in silico ADME profile
We observed intriguing substituent effects in the reaction between 4-substituted
acetophenones and acenaphthenequinone in the presence of KOH in methanol. In all …
acetophenones and acenaphthenequinone in the presence of KOH in methanol. In all …
Design, Synthesis, and Docking Simulation of 1, 3, 4-Thiadiazolyl-Isoindole Thioglycosides and Hydrazinyl Sugar Analogs as Potential Anticancer Agents Targeting …
The development of efficient strategies for overcoming cancer remains a standing objective
in medicinal chemistry. Design and synthesis of new potent compounds contribute efficiently …
in medicinal chemistry. Design and synthesis of new potent compounds contribute efficiently …
Investigation of cytotoxic properties of some isoindole-related compounds bearing silyl and azide groups with in vitro and in silico studies
This study aims to evaluate the synthesis of isoindole-1, 3-dione analogues and their
cytotoxic potential. A549 and HeLa cells exposed to 250–100–50–25 µM doses of each …
cytotoxic potential. A549 and HeLa cells exposed to 250–100–50–25 µM doses of each …
Synthesis, Characterization, and Biological Evaluation of Some Isoindole‐1, 3‐(2H) Dione Derivatives
In this study, we have established promising drug candidates with approved antimicrobial,
antioxidant, antileishmanial, and anticancer activities. We hereby report drug likeliness …
antioxidant, antileishmanial, and anticancer activities. We hereby report drug likeliness …
[PDF][PDF] MOLECULAR DOCKING STUDIES OF 3ꞌ, 5ꞌ-DICHOLORO-2ꞌ-HYDROXYACETOPHENONE-3-METHOXYBENZHYDRAZONE HYDRATE TOWARDS 1JXA …
D Kuriakose, MRP Kurup - Xaverian Research Journal - stxaviersaluva.ac.in
MOLECULAR DOCKING STUDIES OF 3ꞌ, 5ꞌ-DICHOLORO-2ꞌ-HYDROXYACETOPHENONE-3-METHOXYBENZHYDRAZONE
HYDRATE TOWARDS 1JXA RECEPTOR PROTEIN Page 58 DISCOURSE Xaverian …
HYDRATE TOWARDS 1JXA RECEPTOR PROTEIN Page 58 DISCOURSE Xaverian …