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Recent advances in organocatalytic methods for the synthesis of disubstituted 2-and 3-indolinones
R Dalpozzo, G Bartoli, G Bencivenni - Chemical Society Reviews, 2012 - pubs.rsc.org
In recent years, organocatalysis has enhanced its importance as a tool for the synthesis of
enantiomerically enriched compounds. Among the candidates for organocatalysis, the …
enantiomerically enriched compounds. Among the candidates for organocatalysis, the …
Catalytic asymmetric synthesis of oxindoles bearing a tetrasubstituted stereocenter at the C‐3 position
F Zhou, YL Liu, J Zhou - Advanced Synthesis & Catalysis, 2010 - Wiley Online Library
Abstract The 3, 3′‐disubstituted oxindole structural motif is a prominent feature in many
alkaloid natural products, which include all kinds of tetrasubstituted carbon stereocenters …
alkaloid natural products, which include all kinds of tetrasubstituted carbon stereocenters …
Additive effects on asymmetric catalysis
L Hong, W Sun, D Yang, G Li, R Wang - Chemical Reviews, 2016 - ACS Publications
This review highlights a number of additives that can be used to make asymmetric reactions
perfect. Without changing other reaction conditions, simply adding additives can lead to …
perfect. Without changing other reaction conditions, simply adding additives can lead to …
Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action
K Shen, X Liu, L Lin, X Feng - Chemical Science, 2012 - pubs.rsc.org
The enantioselective synthesis of 3-functionalized oxindole derivatives has experienced an
explosive development. This minireview introduces the recent application of rare earth (RE) …
explosive development. This minireview introduces the recent application of rare earth (RE) …
Asymmetric organocatalysis in total synthesis–a trial by fire
E Marqués-López, RP Herrera… - Natural Product …, 2010 - pubs.rsc.org
Covering: 2007 to 2009 This review covers the most recent applications of organocatalysis
in the synthesis of natural products and non-natural biologically active molecules. Our aim is …
in the synthesis of natural products and non-natural biologically active molecules. Our aim is …
Enantioselective Synthesis of AG‐041R by using N‐Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts
N Hara, S Nakamura, M Sano, R Tamura… - … A European Journal, 2012 - Wiley Online Library
The organocatalytic enantioselective decarboxylative addition of malonic acid half thioesters
to ketimines derived from isatins by using N‐heteroarenesulfonyl cinchona alkaloid amides …
to ketimines derived from isatins by using N‐heteroarenesulfonyl cinchona alkaloid amides …
Organocatalytic asymmetric synthesis of substituted 3-hydroxy-2-oxindoles via Morita− Baylis− Hillman reaction
We report a highly enantioselective Morita− Baylis− Hillman (MBH) reaction of isatins and
acrolein to provide enantiomerically enriched 3-substituted 3-hydroxyoxindoles, which could …
acrolein to provide enantiomerically enriched 3-substituted 3-hydroxyoxindoles, which could …
Asymmetric Aldol Reaction of Acetaldehyde and Isatin Derivatives for the Total Syntheses of ent-Convolutamydine E and CPC-1 and a Half Fragment of Madindoline …
T Itoh, H Ishikawa, Y Hayashi - Organic letters, 2009 - ACS Publications
The asymmetric aldol reaction of isatin derivatives and acetaldehyde has been developed
using 4-hydroxydiarylprolinol as a catalyst, affording the aldol products with high …
using 4-hydroxydiarylprolinol as a catalyst, affording the aldol products with high …
Organocatalytic direct asymmetric aldol reactions of 3-isothiocyanato oxindoles to ketones: stereocontrolled synthesis of spirooxindoles bearing highly congested …
WB Chen, ZJ Wu, J Hu, LF Cun, XM Zhang… - Organic …, 2011 - ACS Publications
The first example of a direct catalytic asymmetric intermolecular aldol reaction of 3-
isothiocyanato oxindoles to simple ketones with bifunctional thiourea-tertiary amine as …
isothiocyanato oxindoles to simple ketones with bifunctional thiourea-tertiary amine as …
Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Brønsted Acid Catalyzed sp3 C–H Functionalization
R Niu, J **ao, T Liang, X Li - Organic Letters, 2012 - ACS Publications
Brønsted acid catalyzed functionalization of sp3 C–H bonds in 2-methyl azaarenes has
been achieved in the reaction with isatins. This method provides facile synthesis of …
been achieved in the reaction with isatins. This method provides facile synthesis of …