Neuroblastoma: biology, prognosis, and treatment

JR Park, A Eggert, H Caron - Hematology/oncology clinics of North America, 2010 - Elsevier
Neuroblastoma, a neoplasm of the sympathetic nervous system, is the second most common
extracranial malignant tumor of childhood and the most common solid tumor of infancy …

Neuroblastoma: paradigm for precision medicine

MS Irwin, JR Park - Pediatric Clinics, 2015 - pediatric.theclinics.com
Neuroblastoma (NB), the most common extracranial tumor of childhood, is a cancer of
primordial neural crest cells that give rise to sympathetic neural ganglia and adrenal …

Identification of ALK as a major familial neuroblastoma predisposition gene

YP Mossé, M Laudenslager, L Longo, KA Cole… - Nature, 2008 - nature.com
Neuroblastoma is a childhood cancer that can be inherited, but the genetic aetiology is
largely unknown. Here we show that germline mutations in the anaplastic lymphoma kinase …

Retinoblastoma and neuroblastoma predisposition and surveillance

J Kamihara, F Bourdeaut, WD Foulkes… - Clinical Cancer …, 2017 - AACR
Retinoblastoma (RB) is the most common intraocular malignancy in childhood.
Approximately 40% of retinoblastomas are hereditary and due to germline mutations in the …

Neuroblastoma: biology, prognosis, and treatment

JR Park, A Eggert, H Caron - Pediatric Clinics of North America, 2008 - Elsevier
Neuroblastoma, a neoplasm of the sympathetic nervous system, is the second most common
extracranial malignant tumor of childhood and the most common solid tumor of infancy …

Chromosome 6p22 locus associated with clinically aggressive neuroblastoma

JM Maris, YP Mosse, JP Bradfield, C Hou… - … England Journal of …, 2008 - Mass Medical Soc
Background Neuroblastoma is a malignant condition of the develo** sympathetic nervous
system that most commonly affects young children and is often lethal. Its cause is not known …

Genetic predisposition and chromosome instability in neuroblastoma

GP Tonini, M Capasso - Cancer and Metastasis Reviews, 2020 - Springer
Neuroblastoma (NB) is a pediatric tumor of embryonic origin. About 1–2% of all NBs are
familial cases, and genetic predisposition is suspected for the remaining cases. During the …

The epidemiology of neuroblastoma: a review

JE Heck, B Ritz, RJ Hung, M Hashibe… - Paediatric and …, 2009 - Wiley Online Library
Neuroblastoma is the most common tumour in children less than 1 year of age. The goal of
this review was to summarise the existing epidemiological research on risk factors for …

Neuroblastoma (Peripheral neuroblastic tumours)

R Luksch, MR Castellani, P Collini… - Critical reviews in …, 2016 - Elsevier
Peripheral neuroblastic tumours (PNTs), a family of tumours arising in the embryonal
remnants of the sympathetic nervous system, account for 7–10% of all tumours in children. In …

[HTML][HTML] Cancer stem cells in neuroblastoma therapy resistance

N Aravindan, D Jain, DB Somasundaram… - Cancer Drug …, 2019 - ncbi.nlm.nih.gov
Neuroblastoma (NB) is the most common cancer of infancy and accounts for nearly one
tenth of pediatric cancer deaths. This mortality rate has been attributed to the> 50 …