Precision medicine is increasingly recognized as a promising approach to improve disease
treatment, taking into consideration the individual clinical and biological characteristics …

There are currently no validated treatment biomarkers in psychiatry. Resting State
Functional Connectivity (RSFC) is a popular method for investigating the neural correlates of …

Bipolar disorder (BD) is a psychiatric condition characterized by depressive and manic
episodes that affect 2% of the world population. The first-line long-term treatment for mood …

G protein coupled receptors (GPCRs) are the main mediators of signal transduction in the
central nervous system. Therefore, it is not surprising that many GPCRs have long been …

Rapidly accumulating data from mobile assessments are facilitating our ability to track
patterns of emotions, behaviors, biologic rhythms, and their contextual influences in real …

Background Smartphones and wearable biosensors can continuously and passively
measure aspects of behavior and physiology while also collecting data that require user …

Bipolar disorder (BD) is a complex neurobiological disorder characterized by a pathologic
mood swing. Digital phenoty**, defined as the 'moment-by-moment quantification of the …

Objectives Circadian rhythm disruption is commonly reported in patients with bipolar
disorder. Lithium has been suggested to have effects on the circadian clock, the biological …

Abstract The term 'Digital Phenoty**'has started to appear with increasing regularity in
medical research, especially within psychiatry. This aims to bring together digital traces (eg …

Objective To identify possible socio-demographic and clinical factors associated with Good
Outcome (GO) as compared with Poor Outcome (PO) in adult patients diagnosed with …