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Bacterial origins of human cell-autonomous innate immune mechanisms
The cell-autonomous innate immune system enables animal cells to resist viral infection.
This system comprises an array of sensors that, after detecting viral molecules, activate the …
This system comprises an array of sensors that, after detecting viral molecules, activate the …
Coevolutionary theory of hosts and parasites
Host and parasite evolution are closely intertwined, with selection for adaptations and
counter‐adaptations forming a coevolutionary feedback loop. Coevolutionary dynamics are …
counter‐adaptations forming a coevolutionary feedback loop. Coevolutionary dynamics are …
Higher-order organization of multivariate time series
Time series analysis has proven to be a powerful method to characterize several
phenomena in biology, neuroscience and economics, and to understand some of their …
phenomena in biology, neuroscience and economics, and to understand some of their …
Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell
Cryptosporidium is a leading cause of diarrheal disease in children and an important
contributor to early childhood mortality. The parasite invades and extensively remodels …
contributor to early childhood mortality. The parasite invades and extensively remodels …
Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean
Balancing selection is an evolutionary process that maintains genetic polymorphisms at
selected loci and strongly reduces the likelihood of allele fixation. When allelic …
selected loci and strongly reduces the likelihood of allele fixation. When allelic …
Inferring balancing selection from genome-scale data
The identification of genomic regions and genes that have evolved under natural selection is
a fundamental objective in the field of evolutionary genetics. While various approaches have …
a fundamental objective in the field of evolutionary genetics. While various approaches have …
An overview of current population genomics methods for the analysis of whole‐genome resequencing data in eukaryotes
Characterizing the population history of a species and identifying loci underlying local
adaptation is crucial in functional ecology, evolutionary biology, conservation and …
adaptation is crucial in functional ecology, evolutionary biology, conservation and …
The germ theory revisited: A noncentric view on infection outcome
The germ theory states that pathogenic microorganisms are responsible for causing
infectious diseases. The theory is inherently microbe-centric and does not account for …
infectious diseases. The theory is inherently microbe-centric and does not account for …
Evolutionary gain and loss of a pathological immune response to parasitism
Parasites impose fitness costs on their hosts. Biologists often assume that natural selection
favors infection-resistant hosts. Yet, when the immune response itself is costly, theory …
favors infection-resistant hosts. Yet, when the immune response itself is costly, theory …
Analysis of 427 genomes reveals moso bamboo population structure and genetic basis of property traits
H Zhao, S Sun, Y Ding, Y Wang, X Yue, X Du… - Nature …, 2021 - nature.com
Moso bamboo (Phyllostachys edulis) is an economically and ecologically important
nontimber forestry species. Further development of this species as a sustainable bamboo …
nontimber forestry species. Further development of this species as a sustainable bamboo …