Bacterial origins of human cell-autonomous innate immune mechanisms

T Wein, R Sorek - Nature Reviews Immunology, 2022 - nature.com
The cell-autonomous innate immune system enables animal cells to resist viral infection.
This system comprises an array of sensors that, after detecting viral molecules, activate the …

Coevolutionary theory of hosts and parasites

LJ Buckingham, B Ashby - Journal of Evolutionary Biology, 2022 - academic.oup.com
Host and parasite evolution are closely intertwined, with selection for adaptations and
counter‐adaptations forming a coevolutionary feedback loop. Coevolutionary dynamics are …

Higher-order organization of multivariate time series

A Santoro, F Battiston, G Petri, E Amico - Nature Physics, 2023 - nature.com
Time series analysis has proven to be a powerful method to characterize several
phenomena in biology, neuroscience and economics, and to understand some of their …

Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell

A Guérin, KM Strelau, K Barylyuk, BA Wallbank… - Cell host & …, 2023 - cell.com
Cryptosporidium is a leading cause of diarrheal disease in children and an important
contributor to early childhood mortality. The parasite invades and extensively remodels …

Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean

L Cornetti, PD Fields, L Du Pasquier, D Ebert - Nature Communications, 2024 - nature.com
Balancing selection is an evolutionary process that maintains genetic polymorphisms at
selected loci and strongly reduces the likelihood of allele fixation. When allelic …

Inferring balancing selection from genome-scale data

BD Bitarello, DYC Brandt, D Meyer… - Genome biology and …, 2023 - academic.oup.com
The identification of genomic regions and genes that have evolved under natural selection is
a fundamental objective in the field of evolutionary genetics. While various approaches have …

An overview of current population genomics methods for the analysis of whole‐genome resequencing data in eukaryotes

YXC Bourgeois, BH Warren - Molecular Ecology, 2021 - Wiley Online Library
Characterizing the population history of a species and identifying loci underlying local
adaptation is crucial in functional ecology, evolutionary biology, conservation and …

The germ theory revisited: A noncentric view on infection outcome

F Carlsson, L Råberg - Proceedings of the National Academy of Sciences, 2024 - pnas.org
The germ theory states that pathogenic microorganisms are responsible for causing
infectious diseases. The theory is inherently microbe-centric and does not account for …

Evolutionary gain and loss of a pathological immune response to parasitism

JN Weber, NC Steinel, F Peng, KC Shim, BK Lohman… - Science, 2022 - science.org
Parasites impose fitness costs on their hosts. Biologists often assume that natural selection
favors infection-resistant hosts. Yet, when the immune response itself is costly, theory …

Analysis of 427 genomes reveals moso bamboo population structure and genetic basis of property traits

H Zhao, S Sun, Y Ding, Y Wang, X Yue, X Du… - Nature …, 2021 - nature.com
Moso bamboo (Phyllostachys edulis) is an economically and ecologically important
nontimber forestry species. Further development of this species as a sustainable bamboo …