Biodegradable polymeric nanoparticles based drug delivery systems

A Kumari, SK Yadav, SC Yadav - Colloids and surfaces B: biointerfaces, 2010 - Elsevier
Biodegradable nanoparticles have been used frequently as drug delivery vehicles due to its
grand bioavailability, better encapsulation, control release and less toxic properties. Various …

Biodegradable polymers in drug delivery and oral vaccination

P Jana, M Shyam, S Singh, V Jayaprakash… - European Polymer …, 2021 - Elsevier
Over the years biodegradable polymers have emerged as promising polymeric materials in
drug delivery and vaccination due to their fascinating properties like biocompatibility …

Microencapsulation techniques, factors influencing encapsulation efficiency

NVN Jyothi, PM Prasanna, SN Sakarkar… - Journal of …, 2010 - Taylor & Francis
Microencapsulation is one of the quality preservation techniques of sensitive substances
and a method for production of materials with new valuable properties. Microencapsulation …

Pharmaceutical Particle Engineering via Spray Drying

R Vehring - Pharmaceutical research, 2008 - Springer
This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …

PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases

X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives

RC Mundargi, VR Babu, V Rangaswamy… - Journal of Controlled …, 2008 - Elsevier
Biodegradable nano/microparticles of poly (d, l-lactide-co-glycolide)(PLGA) and PLGA-
based polymers are widely explored as carriers for controlled delivery of macromolecular …

Biodegradable botulinum toxin implant

S Donovan - US Patent 6,506,399, 2003 - Google Patents
BACKGROUND The present invention relates to an implantable drug delivery System. In
particular, the present invention relates to an implantable botulinum toxin delivery System. A …

Control of encapsulation efficiency and initial burst in polymeric microparticle systems

Y Yeo, K Park - Archives of pharmacal research, 2004 - Springer
Initial burst is one of the major challenges in protein-encapsulated microparticle systems.
Since protein release during the initial stage depends mostly on the diffusional escape of the …

Pathogen recognition and development of particulate vaccines: does size matter?

SD **ang, A Scholzen, G Minigo, C David… - Methods, 2006 - Elsevier
The use of particulate carriers holds great promise for the development of effective and
affordable recombinant vaccines. Rational development requires a detailed understanding …

Protein instability in poly (lactic-co-glycolic acid) microparticles

M van de Weert, WE Hennink, W Jiskoot - Pharmaceutical research, 2000 - Springer
In this review the current knowledge of protein degradation during preparation, storage and
release from poly (lactic-co-glycolic acid)(PLGA) microparticles is described, as well as …