Multifaceted roles of flavonoids mediating plant-microbe interactions

L Wang, M Chen, PY Lam, F Dini-Andreote, L Dai… - Microbiome, 2022 - Springer
Plant-microbe interactions dynamically affect plant growth, health, and development. The
mechanisms underpinning these associations are—to a large extent—mediated by …

[HTML][HTML] Flavonoids as important molecules of plant interactions with the environment

J Mierziak, K Kostyn, A Kulma - Molecules, 2014 - mdpi.com
Flavonoids are small molecular secondary metabolites synthesized by plants with various
biological activities. Due to their physical and biochemical properties, they are capable of …

Translating eco-evolutionary biology into therapy to tackle antibiotic resistance

F Sanz-García, T Gil-Gil, P Laborda, P Blanco… - Nature Reviews …, 2023 - nature.com
Antibiotic resistance is currently one of the most important public health problems. The
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …

Ultraviolet radiation from a plant perspective: The plant-microorganism context

L Vanhaelewyn, D Van Der Straeten… - Frontiers in plant …, 2020 - frontiersin.org
Ultraviolet (UV) radiation directly affects plants and microorganisms, but also alters the
species-specific interactions between them. The distinct bands of UV radiation, UV-A, UV-B …

Transcriptome landscape of a bacterial pathogen under plant immunity

T Nobori, AC Velásquez, J Wu, BH Kvitko… - Proceedings of the …, 2018 - pnas.org
Plant pathogens can cause serious diseases that impact global agriculture. The plant innate
immunity, when fully activated, can halt pathogen growth in plants. Despite extensive studies …

Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence

M Alcalde-Rico, S Hernando-Amado, P Blanco… - Frontiers in …, 2016 - frontiersin.org
Multidrug efflux pumps can be involved in bacterial resistance to antibiotics at different
levels. Some efflux pumps are constitutively expressed at low levels and contribute to …

[HTML][HTML] Pseudomonas aeruginosa: an antibiotic resilient pathogen with environmental origin

P Laborda, F Sanz-García, S Hernando-Amado… - Current Opinion in …, 2021 - Elsevier
Highlights•P. aeruginosa is opportunistic pathogen with an environmental origin.•P.
aeruginosa presents low susceptibility to currently used antibiotics.•P. aeruginosa displays a …

[HTML][HTML] Coming from the wild: multidrug resistant opportunistic pathogens presenting a primary, not human-linked, environmental habitat

F Sanz-García, T Gil-Gil, P Laborda… - International Journal of …, 2021 - mdpi.com
The use and misuse of antibiotics have made antibiotic-resistant bacteria widespread
nowadays, constituting one of the most relevant challenges for human health at present …

[HTML][HTML] An Arabidopsis secondary metabolite directly targets expression of the bacterial type III secretion system to inhibit bacterial virulence

W Wang, J Yang, J Zhang, YX Liu, C Tian, B Qu… - Cell host & …, 2020 - cell.com
Plants deploy a variety of secondary metabolites to fend off pathogen attack. Although
defense compounds are generally considered toxic to microbes, the exact mechanisms are …

Antibacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates

LK Tsou, M Lara-Tejero, J RoseFigura… - Journal of the …, 2016 - ACS Publications
Traditional Chinese Medicines (TCMs) have been historically used to treat bacterial
infections. However, the molecules responsible for these anti-infective properties and their …