l-Ascorbic acid (ASA), vitamin C, is a ubiquitous carbohydrate-like compound that has an
essential role in a number of cellular processes, such as collagen synthesis, cellular …

Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various
developments to prevent and treat cancer, the side effects of anticancer drugs remain a …

Coumarin enjoys an important place in drug discovery process due to its presence in
diversity of biologically active compounds. Many compounds of plant origin are derivatives …

Several novel 1, 2, 4-triazole and imidazole l-ascorbic acid (1, 2, 3, 5, 6 and 9) and imino-
ascorbic acid (4, 7 and 8) derivatives were prepared and evaluated for their inhibitory activity …

Abstract Regioselective 1, 4-disubstituted 1, 2, 3-triazole tethered pyrimidine-2, 4-dione
derivatives (5–23) were successfully prepared by the copper (I)-catalyzed click chemistry …

Abstract Two series of 6-(1, 2, 3-triazolyl)-2, 3-dibenzyl-l-ascorbic acid derivatives with the
hydroxyethylene (8a− 8u) and ethylidene linkers (10c− 10p) were synthesized and …

The pyrimidine heterocycle plays an important role in anticancer research. In particular, the
pyrimidine derivative families of uracil show promise as structural scaffolds relevant to …

Since the influenza viruses can rapidly evolve, it is urgently required to develop novel anti-
influenza agents possessing a novel mechanism of action. In our previous study, two …

The present article describes the synthesis of dihydrobenzo [4, 5] imidazo [1, 2-a] pyrimidin-
4-one (2a–h) under microwave irradiation. The product was obtained in excellent yield (74 …

L-Ascorbic acid, commonly known as vitamin C is well-known in chemistry since long back. It
has tremendous medical applications in several diseases. However, application of this chiral …