Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at
an unprecedented temporal precision for neurological disorders. This has the potential to …

Two decades of cross-species neuroscience research on rapid action-stop** in the
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …

Objective. Technical advances in deep brain stimulation (DBS) are crucial to improve
therapeutic efficacy and battery life. We report the potentialities and pitfalls of one of the first …

Compared to other neurodegenerative diseases, Parkinson's disease (PD) is distinctive in
terms of marked symptomatic variability and prognosis, as well as for the wide variety of …

Disruption of subthalamic nucleus dynamics in Parkinson's disease leads to impairments
during walking. Here, we aimed to uncover the principles through which the subthalamic …

Freezing of gait is a debilitating symptom in advanced Parkinson's disease and responds
heterogeneously to treatments such as deep brain stimulation. Recent studies indicated that …

This review is part of the series on the clinical neurophysiology of movement disorders. It
focuses on Parkinson's disease and parkinsonism. The topics covered include the …

Freezing of Gait (FoG) is a movement disorder that mostly appears in the late stages of
Parkinson's Disease (PD). It causes incapability of walking, despite the PD patient's …

This manuscript is the second part of a two-part description of the current status of
understanding of the network function of the brain in health and disease. We start with the …

Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …