A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

RS Keri, MR Patil, SA Patil, S Budagumpi - European Journal of Medicinal …, 2015 - Elsevier
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

Medicinal significance of benzothiazole scaffold: an insight view

PC Sharma, A Sinhmar, A Sharma… - Journal of enzyme …, 2013 - Taylor & Francis
Heterocycles bearing nitrogen, sulphur and thiazole moieties constitute the core structure of
a number of biologically interesting compounds. Benzothiazole, a group of xenobiotic …

Synthesis and antimicrobial activity of some new thiazole, thiophene and pyrazole derivatives containing benzothiazole moiety

S Bondock, W Fadaly, MA Metwally - European journal of medicinal …, 2010 - Elsevier
In an attempt to find a new class of antimicrobial agents, a series of thiazole, thiophene,
pyrazole and other related products containing benzothiazole moiety were prepared via the …

Synthesis and antitumor evaluation of some new 1, 3, 4-oxadiazole-based heterocycles

S Bondock, S Adel, HA Etman, FA Badria - European journal of medicinal …, 2012 - Elsevier
The synthetic strategies and characterization of some novel 1, 3, 4-oxadiazole derivatives
carrying different pharmacophores and heterocyclic rings that are relevant to potential …

Synthesis and evaluation of antioxidant and antibacterial activities of new substituted bis (1, 3, 4-oxadiazoles), 3, 5-bis (substituted) pyrazoles and isoxazoles

EA Musad, R Mohamed, BA Saeed… - Bioorganic & medicinal …, 2011 - Elsevier
Two series of five membered heterocyclic bis (1, 3, 4-oxadiazole) derivatives 2 (a–h) and 3,
5-bis (substituted) pyrazoles, isoxazoles 3 (a, b, d–i), 4 (a–c) were synthesized via oxidative …

Synthesis of some new 2-(3-pyridyl)-4, 5-disubstituted thiazoles as potent antimicrobial agents

S Bondock, T Naser, YA Ammar - European Journal of Medicinal Chemistry, 2013 - Elsevier
As a part of ongoing studies in develo** new potent antimicrobial agents, a series of novel
2-(3-pyridyl)-4, 5-disubstituted thiazoles was efficiently synthesized and characterized by …

[HTML][HTML] Synthetic and biological studies of pyrazolines and related heterocyclic compounds

M Yusuf, P Jain - Arabian Journal of Chemistry, 2014 - Elsevier
This review provides a comprehensive survey relating to the synthesis and biological
applications of pyrazolines and related heterocycles in the last five years (2007–2011) …

Structural activity relationship and importance of benzothiazole derivatives in medicinal chemistry: a comprehensive review

M Bhat, SL Belagali - Mini-Reviews in Organic Chemistry, 2020 - ingentaconnect.com
Benzothiazole (1, 3-benzothiazole) is one of the heterocyclic compounds, which is a weak
base having varied biological activities. The unique methine center present in the thiazole …

[HTML][HTML] Pyrimidine derivatives as selective COX-2 inhibitors with anti-inflammatory and antioxidant properties

B Tylińska, A Janicka-Kłos… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Pyrimidine derivatives exhibit a wide range of biological activities, including anti-
inflammatory properties. The aim of this study was to investigate the effects of tested …

Synthesis and cytotoxic evaluation of thiourea and N-bis-benzothiazole derivatives: A novel class of cytotoxic agents

RM Kumbhare, T Dadmal, U Kosurkar, V Sridhar… - Bioorganic & medicinal …, 2012 - Elsevier
Benzothiazolyl thiocarbamides has been achieved using a catalytic amount of 4-
dimethylaminopyridine (DMAP) followed by its chemoselective oxidative cyclization with 1, 3 …