T11 target structure induced modulations of the pro-inflammatory and anti-infammatorycytokine expressions in experimental animals for glioma abrogation

MK Singh, S Chaudhuri, D Bhattacharya… - International …, 2015 - Elsevier
Glioma angiogenesis is the result of the interaction between cancer cells with endothelial
cells, and the surrounding inflammatory cells. This interaction plays a crucial role in directing …

Akt phosphorylation orchestrates T11TS mediated cell cycle arrest in glioma cells

S Acharya, S Chatterjee, S Chaudhuri… - Cancer …, 2021 - Taylor & Francis
The novel anti-neoplastic glycopeptide T11TS retards glioma both in in-vitro clinical samples
and in-vivo models. This study investigates the correlation between altering the glioma …

Significant modulation of macrophages associated cytokines TNF-α, VEGF and apoptotoic protein Bax, Bcl2 abrogates tumor cells

P Kumar, S Chatterjee, S Acharya, A Kumari… - Cellular …, 2013 - Elsevier
Abstract T11 target structure (T11TS), a membrane glycoprotein has been documented with
anti neoplastic activity in glioma bearing animal model in our lab. In this study, we have …

T11TS immunotherapy potentiates the repressed calcineurin‐NFAT signalling pathway of T cells in Cryptococcus neoformans infected rats: a cue towards T‐cell …

SM Omar Faruk, I Hazra, S Mondal… - Journal of Applied …, 2020 - academic.oup.com
Aims To examine the modulation of the interacting partners of the calcineurin (CaN)‐NFAT
pathway in T cells during Cryptococcus neoformans fungal infection and post‐T11TS …

Therapeutic intervention of glioma with the novel antineoplastic agent T11TS: the story so far

S Chaudhuri, S Acharya, S Chaudhuri - Immunotherapy, 2022 - Taylor & Francis
The disease relevance of novel therapeutic agent T11TS, established first by the authors'
group, was shown to ameliorate experimental glioma through multimodal mechanistic …

T11TS repress gliomagenic apoptosis of bone marrow hematopoietic stem cells

S Mondal, I Hazra, A Datta, OF Sk Md… - Journal of cellular …, 2018 - Wiley Online Library
Combating gliomagenic global immunosuppression is one of the emerging key for
improving prognosis in malignant glioma. Apoptosis plays a pivotal role within the adult …

[PDF][PDF] T11TS Induced Modulation of Macrophages Associated Cytokines TNF-α, VEGF and Apoptototic Protein Bax, Bcl2 Abrogates Tumor Cells in

P Kumar, S Chatterjee, SN Ghosh, S Acharya… - 2013 - academia.edu
Abstract T11 target structure (T11TS), a membrane glycoprotein has been documented with
anti-neoplastic activity in glioma bearing animal model in our lab. In this study, we have …