In vivo and in vitro studies have demonstrated the positive role that ultrasound can play in
the enhancement of fracture healing or in the reactivation of a failed healing process. We …

This chapter reviews the different options available for the use of ultrasound in the
enhancement of fracture healing or in the reactivation of a failed healing process: LIPUS …

Impaired bone-fracture healing is associated with long-term musculoskeletal disability, pain
and psychological distress. Low-intensity pulsed ultrasound (LIPUS) is a non-invasive and …

Quantitative ultrasound (QUS) is a promising technique for bone tissue evaluation. Highly
focused transducers used for QUS also have the capability to be applied for tissue …

We report on the use of elastographic imaging techniques to assess the bone/soft tissue
interface, a region that has not been previously investigated but may provide important …

Iron oxide nanoparticles (IONPs) are becoming increasingly used and intensively
investigated in the field of medical imaging. They are currently FDA approved for magnetic …

In this paper, we investigated the mechanoresponse of C2C12 mesenchymal precursor cells
to focused low-intensity pulsed ultrasound (FLIPUS). The setup has been developed for in …

In the process of fracture healing, several phases of recovery are observed as the
mechanical stability, continuity and normal load carrying capacity are gradually restored …

Holotomography, a phase-sensitive synchrotron-based (µCT) modality, is a quantitative 3D
imaging method. By exploiting partial spatial X-ray coherence, bones can be imaged …

Competent fracture healing monitoring and treatment requires an extensive knowledge of
bone biology and microstructure. The use of non-invasive and non-radiating means for the …