[HTML][HTML] Single-cell metabolomics: where are we and where are we going?

I Lanekoff, VV Sharma, C Marques - Current opinion in biotechnology, 2022 - Elsevier
Single-cell metabolomics with mass spectrometry enables a large variety of metabolites to
be simultaneously detected from individual cells, without any preselection or labelling, to …

Single-cell mass spectrometry

M Tajik, M Baharfar, WA Donald - Trends in Biotechnology, 2022 - cell.com
Owing to recent advances in mass spectrometry (MS), tens to hundreds of proteins, lipids,
and small molecules can be measured in single cells. The ability to characterize the …

CE‐MS for metabolomics: Developments and applications in the period 2018–2020

W Zhang, R Ramautar - Electrophoresis, 2021 - Wiley Online Library
Capillary electrophoresis‐mass spectrometry (CE‐MS) is now a mature analytical technique
in metabolomics, notably for the efficient profiling of polar and charged metabolites. Over the …

[HTML][HTML] The limitless applications of single-cell metabolomics

S Guo, C Zhang, A Le - Current Opinion in Biotechnology, 2021 - Elsevier
Single-cell metabolomics (SCM) is currently one of the most powerful tools for performing
high-throughput metabolic analysis at the cellular level. The power of single-cell …

Microbial metabolomics: From novel technologies to diversified applications

D Ye, X Li, J Shen, X **a - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Microbial metabolomics focuses on the analysis of intracellular or extracellular primary
metabolites, signaling molecules, hormones, and secondary metabolites, and it is an …

Nanofluidic devices and applications for biological analyses

K Yamamoto, N Ota, Y Tanaka - Analytical Chemistry, 2020 - ACS Publications
As analytical interests have become targeted on sensitive detection of objects of a tiny size
and volume, various fields in analytical chemistry have been developed to overcome …

Analysis of peptide stereochemistry in single cells by capillary electrophoresis–trapped ion mobility spectrometry mass spectrometry

DH Mast, HW Liao, EV Romanova… - Analytical …, 2021 - ACS Publications
Single cell analysis strives to probe molecular heterogeneity in morphologically similar cell
populations through quantitative or qualitative measurements of genetic, proteomic, or …

Advances in capillary electrophoresis mass spectrometry for metabolomics

T Soga - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Capillary electrophoresis mass spectrometry (CE-MS) is now regarded as a powerful tool for
the comprehensive analysis of low-molecular-weight charged metabolites. Over the past …

Challenging bioanalyses with capillary electrophoresis

CJ Kristoff, L Bwanali, LM Veltri, GP Gautam… - Analytical …, 2019 - ACS Publications
This report covers advances in capillary electrophoresis (CE) from January 2018 through
September 2019. A summary of the literature during this time period is insightful. A search …

Single-cell metabolite analysis by electrospray ionization mass spectrometry

G Zhu, Y Shao, Y Liu, T Pei, L Li, D Zhang… - TrAC Trends in …, 2021 - Elsevier
Many diseases are related to abnormal metabolites in cells. It is of great significance to
analyze the metabolites for cellular physiological, pathological, and pharmacological …