Life expectancy has increased immensely over the past decades, bringing new challenges
to the health systems as advanced age increases the predisposition for many diseases. One …

The microbiota gut brain (MGB) axis has been shown to play a significant role in the
regulation of inflammatory and infective diseases. Exploring the structure and …

Tertiary lymphoid structures (TLSs) are formed in inflamed tissues, and recent studies
demonstrated that the appearance of TLSs in tumor sites is associated with a good …

A small proportion of multiple sclerosis (MS) patients develop new disease activity soon after
starting anti-CD20 therapy. This activity does not recur with further dosing, possibly reflecting …

Multiple sclerosis (MS) is an immune-mediated disease that targets the myelin sheath of
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) characterized by destruction of the myelin sheath structure. The loss of myelin leads …

Antigen (Ag)-presenting cells capture or synthesize Ags that are processed into peptides
bound and displayed on the plasma membrane by major histocompatibility complex (MHC) …

Introduction Although CD20 is classically a B cell marker, in the last three decades, dim
expression has been noted on a subset of T cells as well that has been independently …

Studies among people with multiple sclerosis (pwMS) receiving disease-modifying therapies
(DMTs) have provided adequate evidence for an appraisal of COVID-19 vaccination policies …

Background Recent studies suggest that extended interval dosing of ocrelizumab, an anti-B
cell therapy, does not affect its clinical effectiveness in most patients with multiple sclerosis …