Recently, it was proposed that there is a common mechanism behind the activity of
bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However …

Mitochondrial metabolism, dynamics, and stress responses in the intestinal stem cell niche
play a pivotal role in regulating intestinal epithelial cell homeostasis, including self-renewal …

Sorafenib is an anti-tumor drug widely used in clinical treatment, which can inhibit tyrosine
kinase receptor on cell surface and serine/threonine kinase in downstream Ras/MAPK …

Due to a long history of improper and excessive use, Penicillin G (Pen G) and erythromycin
(Ery) are regularly detected in environmental samples and pose a great threat to human …

Chronic rhinosinusitis (CRS) is a prevalent inflammatory airway disease affecting over 10%
of the global population, leading to considerable socio-economic impacts, especially in …

The rapid dissemination of antibiotic resistance combined with the decline in the discovery
of novel antibiotics represents a major challenge for infectious disease control that can only …

Introduction: Antibiotics are often administered to patients perioperatively and have been
shown to affect ROS production of nasal cells in vitro, but their effect in the setting of active …

Objective: Previous investigations suggest the use of extract from the root of Pelargonium
sidoides (EPs 7630) for the therapy of uncomplicated acute upper airway inflammations, due …

Bacterial sepsis characterised by an immunosuppressive and cytokine storm state is a
challenge to treat clinically. While conventional antibiotics have been associated with …

Background Environmental factors such as inhaled pollutants like cigarette smoke may play
a significant role in diseases of the upper airway including chronic rhinosinusitis (CRS) …