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Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents
The present work highlights recent achievements in development of nanostructured
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …
Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers
Silk is a unique, remarkably strong biomaterial made of simple protein building blocks. To
date, no synthetic method has come close to reproducing the properties of natural silk, due …
date, no synthetic method has come close to reproducing the properties of natural silk, due …
Insight into structural biophysics from solution X-ray scattering
The current challenges of structural biophysics include determining the structure of large self-
assembled complexes, resolving the structure of ensembles of complex structures and their …
assembled complexes, resolving the structure of ensembles of complex structures and their …
Structure of sodium carboxymethyl cellulose aqueous solutions: A SANS and rheology study
We report a small angle neutron scattering (SANS) and rheology study of cellulose
derivative polyelectrolyte sodium carboxymethyl cellulose with a degree of substitution of …
derivative polyelectrolyte sodium carboxymethyl cellulose with a degree of substitution of …
Using solution X-ray scattering to determine the high-resolution structure and morphology of PEGylated liposomal doxorubicin nanodrugs
Abstract Background Among nanodrugs, PEGylated nanoliposomes loaded with an active
agent are of major importance. In this paper we studied the structures and morphology of …
agent are of major importance. In this paper we studied the structures and morphology of …
RNA encapsidation by SV40-derived nanoparticles follows a rapid two-state mechanism
Remarkably, uniform virus-like particles self-assemble in a process that appears to follow a
rapid kinetic mechanism. The mechanisms by which spherical viruses assemble from …
rapid kinetic mechanism. The mechanisms by which spherical viruses assemble from …
Shape and interhelical spacing of DNA origami nanostructures studied by small-angle X-ray scattering
Scaffolded DNA origami nanostructures enable the self-assembly of arbitrarily shaped
objects with unprecedented accuracy. Yet, varying physiological conditions are prone to …
objects with unprecedented accuracy. Yet, varying physiological conditions are prone to …
Characterization of PEGylated nanoliposomes co-remotely loaded with topotecan and vincristine: relating structure and pharmacokinetics to therapeutic efficacy
Recently, develo** drug delivery systems exhibiting controlled drug release at the tumor
sites emerged as an attractive option for enhancing anticancer therapeutic efficacy. It seems …
sites emerged as an attractive option for enhancing anticancer therapeutic efficacy. It seems …
Assembly reactions of hepatitis B capsid protein into capsid nanoparticles follow a narrow path through a complex reaction landscape
For many viruses, capsids (biological nanoparticles) assemble to protect genetic material
and dissociate to release their cargo. To understand these contradictory properties, we …
and dissociate to release their cargo. To understand these contradictory properties, we …
Vesicle adhesion and fusion studied by small-angle X-ray scattering
K Komorowski, A Salditt, Y Xu, H Yavuz, M Brennich… - Biophysical …, 2018 - cell.com
We have studied the adhesion state (also denoted by docking state) of lipid vesicles as
induced by the divalent ions Ca 2+ or Mg 2+ at well-controlled ion concentration, lipid …
induced by the divalent ions Ca 2+ or Mg 2+ at well-controlled ion concentration, lipid …