Lineage plasticity and histologic transformation to small cell neuroendocrine prostate cancer
(NEPC) is an increasingly recognized mechanism of treatment resistance in advanced …

Biofluid-based biomarker tests hold great promise for precision medicine in prostate cancer
(PCa) clinical practice. Extracellular vesicles (EV) are established as intercellular …

Breast cancer (BC) affects 1 in every 8 women in the United States and is currently the most
prevalent cancer worldwide. Precise staging at diagnosis and prognosis are essential …

Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of less than 10%
due to its late diagnosis, rapid metastasis, and chemotherapeutic resistance. For a small …

Multiple myeloma (MM) is accompanied by alterations to the normal plasma cell (PC)
proteome, leading to changes to the tumor microenvironment and disease progression …

Simple Summary The standard of care for patients diagnosed with upper tract urothelial
carcinoma (UTUC) is surgery. However, the current standard tools for the diagnosis and …

Extracellular vesicles (EVs) are highly abundant in human biofluids, containing a repertoire
of macromolecules and biomarkers representative of the tissue of origin. EVs released by …

Background Post-acute COVID-19 syndrome (PACS) is linked to severe organ damage. The
identification and stratification of at-risk SARS-CoV-2 infected individuals is vital to providing …

Background Large non-apoptotic vesicles released from the plasma membrane protrusions
are classified as large-EVs (LEVs). However, the triggers of LEV secretion and their …

Simple Summary Prostate cancer research has been recently characterized by the discovery
of several prognostic and predictive molecular factors, which ultimately improve patients' …