Mechanisms of clathrin-mediated endocytosis

M Kaksonen, A Roux - Nature reviews Molecular cell biology, 2018 - nature.com
Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

Interplay between mechanics and signalling in regulating cell fate

H De Belly, EK Paluch, KJ Chalut - Nature Reviews Molecular Cell …, 2022 - nature.com
Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

[HTML][HTML] Mechanoresponsive metabolism in cancer cell migration and metastasis

MR Zanotelli, J Zhang, CA Reinhart-King - Cell metabolism, 2021 - cell.com
Altered tissue mechanics and metabolism are defining characteristics of cancer that impact
not only proliferation but also migration. While migrating through a mechanically and …

A fluorescent membrane tension probe

A Colom, E Derivery, S Soleimanpour, C Tomba… - Nature …, 2018 - nature.com
Cells and organelles are delimited by lipid bilayers in which high deformability is essential to
many cell processes, including motility, endocytosis and cell division. Membrane tension is …

[HTML][HTML] Cell protrusions and contractions generate long-range membrane tension propagation

H De Belly, S Yan, HB da Rocha, S Ichbiah, JP Town… - Cell, 2023 - cell.com
Membrane tension is thought to be a long-range integrator of cell physiology. Membrane
tension has been proposed to enable cell polarity during migration through front-back …

[HTML][HTML] Membrane tension gates ERK-mediated regulation of pluripotent cell fate

H De Belly, A Stubb, A Yanagida, C Labouesse… - Cell stem cell, 2021 - cell.com
Cell fate transitions are frequently accompanied by changes in cell shape and mechanics.
However, how cellular mechanics affects the instructive signaling pathways controlling cell …

The plasma membrane as a mechanochemical transducer

AL Le Roux, X Quiroga, N Walani… - … of the Royal …, 2019 - royalsocietypublishing.org
Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

Understanding nanoparticle cellular entry: a physicochemical perspective

CM Beddoes, CP Case, WH Briscoe - Advances in colloid and interface …, 2015 - Elsevier
Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …

[HTML][HTML] Pay attention to membrane tension: Mechanobiology of the cell surface

E Sitarska, A Diz-Muñoz - Current opinion in cell biology, 2020 - Elsevier
The cell surface is a mechanobiological unit that encompasses the plasma membrane, its
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …

[HTML][HTML] Load adaptation of lamellipodial actin networks

J Mueller, G Szep, M Nemethova, I De Vries, AD Lieber… - Cell, 2017 - cell.com
Actin filaments polymerizing against membranes power endocytosis, vesicular traffic, and
cell motility. In vitro reconstitution studies suggest that the structure and the dynamics of actin …