Blood-spinal cord barrier disruption in degenerative cervical myelopathy
HW Kim, H Yong, GKH Shea - Fluids and Barriers of the CNS, 2023 - Springer
Degenerative cervical myelopathy (DCM) is the most prevalent cause of spinal cord
dysfunction in the aging population. Significant neurological deficits may result from a …
dysfunction in the aging population. Significant neurological deficits may result from a …
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression
M Yao, P Pu, Z Li, K Zhu, L Zhou, YL Sun… - Journal of pineal …, 2023 - Wiley Online Library
Cervical spondylotic myelopathy (CSM) refers to a chronic injury of the cervical cord caused
by cervical intervertebral disc degeneration. Endoplasmic reticulum (ER) homeostasis is …
by cervical intervertebral disc degeneration. Endoplasmic reticulum (ER) homeostasis is …
Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice
ZY Li, AF Zhou, G Li, LY Zhou, PM Pu… - Neural Regeneration …, 2023 - journals.lww.com
Chronic spinal cord compression (CSCC) is induced by disc herniation and other reasons,
leading to movement and sensation dysfunction, with a serious impact on quality of life …
leading to movement and sensation dysfunction, with a serious impact on quality of life …
[HTML][HTML] Network pharmacology analysis and animal experiment validation of neuroinflammation inhibition by total ginsenoside in treating CSM
Z Li, Y Dai, Z Wu, G Li, P Pu, C Hu, L Zhou, K Zhu… - Phytomedicine, 2024 - Elsevier
Background Cervical spondylotic myelopathy (CSM) is a degenerative pathology that affects
both upper and lower extremity mobility and sensory function, causing significant pressure …
both upper and lower extremity mobility and sensory function, causing significant pressure …
Shenqisherong pill ameliorates neuronal apoptosis by inhibiting the JNK/caspase-3 signaling pathway in a rat model of cervical cord compression
K Zhu, P Pu, G Li, L Zhou, Z Li, Q Shi, Y Wang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The Shenqisherong (SQSR) pill is an empirical
prescription of traditional Chinese medicine (TCM), which originated from the National …
prescription of traditional Chinese medicine (TCM), which originated from the National …
Shikonin inhibits endoplasmic reticulum stress-induced apoptosis to attenuate renal ischemia/reperfusion injury by activating the SIRT1/Nrf2/HO-1 pathway
Q Huang, Z Shi, D Zheng, H Chen… - Kidney and Blood Pressure …, 2025 - karger.com
Introduction: Shikonin is the major bioactive compound abundant in Lithospermum
erythrorhizon and possesses diverse pharmacological properties. This study aimed to …
erythrorhizon and possesses diverse pharmacological properties. This study aimed to …
Ischemia–reperfusion injury after spinal cord decompressive surgery—An in vivo rat model
B Zhang, Z **, P Luo, H Yin, X Chen… - Animal Models and …, 2024 - Wiley Online Library
Background Although decompression surgery is the optimal treatment for patients with
severe degenerative cervical myelopathy (DCM), some individuals experience no …
severe degenerative cervical myelopathy (DCM), some individuals experience no …
[HTML][HTML] Analysis of gene expression profiles and experimental validations of a rat chronic cervical cord compression model
P Pu, Z Li, Y Dai, Y Sun, Y Wang, X Cui… - Neurochemistry …, 2023 - Elsevier
Cervical spondylotic myelopathy (CSM) is a severe non-traumatic spinal cord injury (SCI)
wherein the spinal canal and cervical cord are compressed due to the degeneration of …
wherein the spinal canal and cervical cord are compressed due to the degeneration of …
Finite element biomechanical analysis of minimally invasive treatment of cervical spondylotic myelopathy and accurate exercise rehabilitation
J Liu, H Zhang, H Cui, L Pan, B Zhao, F Li… - Chinese Journal of Tissue …, 2023 - cjter.com
BACKGROUND: Endoscopic fenestration and decompression of cervical lamina lead to
changes in bony structure of cervical vertebrae, which in turn leads to biomechanical …
changes in bony structure of cervical vertebrae, which in turn leads to biomechanical …
Natural agents that are neuroprotective against mitochondria: a bibliometric-based research map** 1998–2024, from cells to mitochondria
Introduction Mitochondria are cell organelles that function as the cell's main power plant,
producing ATP, the main energy molecule in cells. Mitochondria play an important role in the …
producing ATP, the main energy molecule in cells. Mitochondria play an important role in the …