Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate
into the esophagus or beyond, resulting in either troublesome symptoms or complications …

Background Gastro‐oesophageal reflux disease (GORD) is a common condition with 3% to
33% of people from different parts of the world suffering from GORD. There is considerable …

Background Randomised controlled trials of healthcare interventions depend on the
participation of volunteers who might not derive any personal health benefit from their …

Objectives: Transoral incisionless fundoplication (TIF) was developed in an attempt to create
a minimally invasive endoscopic procedure that mimics antireflux surgery. The objective of …

Background This randomized clinical trial compared long-term outcome after antireflux
surgery with acid inhibition therapy in the treatment of chronic gastro-oesophageal reflux …

Background Laparoscopic antireflux surgery (LARS) represents the gold standard in the
treatment of gastroesophageal reflux disease with or without hiatal hernia. It offers excellent …

Background A novel transoral incisionless fundoplication (TIF) procedure using the EsophyX
system with SerosaFuse fasteners was designed to reconstruct a full-thickness valve at the …

Laparoscopic Nissen fundoplication and proton pump inhibitor (PPI) therapy are both
established treatments for gastroesophageal reflux disease (GERD). We have performed a …

Background There are several options for the surgical management of GERD in adults.
Previous guidelines and systematic reviews have compared the effects of total …

BACKGROUND Despite promising evidence that laparoscopic fundoplication provides
better short-term relief of gastro-oesophageal reflux disease (GORD) than continued …