Nanotherapeutics with immunoregulatory functions for the treatment of bacterial infection
The advent of drug-resistant pathogens results in the occurrence of stubborn bacterial
infections that cannot be treated with traditional antibiotics. Antibacterial immunotherapy by …
infections that cannot be treated with traditional antibiotics. Antibacterial immunotherapy by …
The emergence of cancer sono-immunotherapy
Y Yang, Y Cheng, L Cheng - Trends in Immunology, 2024 - cell.com
Owing to its remarkable ease of use, ultrasound has recently been explored for stimulating
or amplifying immune responses during cancer therapy, termed 'sono-immunotherapy' …
or amplifying immune responses during cancer therapy, termed 'sono-immunotherapy' …
Supramolecular Photothermal Cascade Nano‐Reactor Enables Photothermal Effect, Cascade Reaction, and In Situ Hydrogelation for Biofilm‐Associated Tooth …
Due to the emergence of drug resistance in bacteria and biofilm protection, achieving a
satisfactory therapeutic effect for bacteria‐infected open wounds with conventional …
satisfactory therapeutic effect for bacteria‐infected open wounds with conventional …
Biomaterials for in situ cell therapy
Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …
Immunomodulatory biomaterials against bacterial infections: Progress, challenges, and future perspectives
Bacterial infectious diseases are one of the leading causes of death worldwide. Even with
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …
Macrophage-membrane-camouflaged nonviral gene vectors for the treatment of multidrug-resistant bacterial sepsis
H Cao, Y Gao, H Jia, L Zhang, J Liu, G Mu, H Gui… - Nano Letters, 2022 - ACS Publications
Sepsis is a life-threatening disease caused by systemic bacterial infections, with high
morbidity and mortality worldwide. As the standard treatment for sepsis, antibiotic therapy …
morbidity and mortality worldwide. As the standard treatment for sepsis, antibiotic therapy …
A natural killer cell mimic against intracellular pathogen infections
In the competition between the pathogen infection and the host defense, infectious
microorganisms may enter the host cells by evading host defense mechanisms and use the …
microorganisms may enter the host cells by evading host defense mechanisms and use the …
PTT/PDT-induced microbial apoptosis and wound healing depend on immune activation and macrophage phenotype transformation
H Chen, L Wu, T Wang, F Zhang, J Song, J Fu, X Kong… - Acta biomaterialia, 2023 - Elsevier
Antibiotics show unsuccessful application in biofilm destruction, which induce chronic
infections and emergence of antibiotic resistant bacteria. Photodynamic therapy (PDT) and …
infections and emergence of antibiotic resistant bacteria. Photodynamic therapy (PDT) and …
Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria
The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …
resistance create a global health concern. The challenge lies in the unique Gram-negative …
[HTML][HTML] Metal-fluorouracil networks with disruption of mitochondrion enhanced ferroptosis for synergistic immune activation
Rationale: Ferroptosis drugs inducing cancer immunogenic cell death (ICD) have shown the
potential of immunotherapy in vivo. However, the current ferroptosis drugs usually induce …
potential of immunotherapy in vivo. However, the current ferroptosis drugs usually induce …