Detergent-free isolation of membrane proteins and strategies to study them in a near-native membrane environment
B Krishnarjuna, A Ramamoorthy - Biomolecules, 2022 - mdpi.com
Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …
membrane environment are important to fully understand their biological function and the …
Alzheimer's disease: The role of proteins in formation, mechanisms, and new therapeutic approaches
A Gholami - Neuroscience Letters, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurological disorder that affects the central
nervous system (CNS), leading to memory and cognitive decline. In AD, the brain …
nervous system (CNS), leading to memory and cognitive decline. In AD, the brain …
Enhancing the stability and homogeneity of non-ionic polymer nanodiscs by tuning electrostatic interactions
The nanodisc technology is increasingly used for structural studies on membrane proteins
and drug delivery. The development of synthetic polymer nanodiscs and the recent …
and drug delivery. The development of synthetic polymer nanodiscs and the recent …
Sulfonated polystyrenes: pH and Mg2+-insensitive amphiphilic copolymers for detergent-free membrane protein isolation
M Janata, S Gupta, E Čadová, P Angelisová… - European Polymer …, 2023 - Elsevier
Amphiphilic polymers are increasingly applied in the detergent-free isolation and functional
studies of membrane proteins. However, the carboxylate group present in the structure of …
studies of membrane proteins. However, the carboxylate group present in the structure of …
Nanogels, nanodiscs, yeast cells, and metallo-complexes-based curcumin delivery for therapeutic applications
M Rahmanian, F Oroojalian, E Pishavar… - European Polymer …, 2023 - Elsevier
Curcumin extracted from the rhizomes of Curcuma longa and widely used because of its
biological advantages such as anti-inflammatory, anti-cancer, anti-oxidant, anti-ageing, anti …
biological advantages such as anti-inflammatory, anti-cancer, anti-oxidant, anti-ageing, anti …
[HTML][HTML] Characterization of size-tuneable aescin-lipid nanoparticles as platform for stabilization of membrane proteins
F Escobedo, M Gospalswamy, P Hägerbäumer… - Colloids and Surfaces B …, 2024 - Elsevier
Disc-like lipid nanoparticles stabilized by saponin biosurfactants display fascinating
properties, including their temperature-driven re-organization. β-Aescin, a saponin from …
properties, including their temperature-driven re-organization. β-Aescin, a saponin from …
An Acrylonitrile‐Based Copolymer Gel as an NMR Alignment Medium for Extraction of Residual Dipolar Couplings of Small Molecules in Aqueous Solution
DS Carvalho, DGB da Silva, F Hallwass… - …, 2023 - Wiley Online Library
An NMR weakly‐aligning polymer gel has been prepared by copolymerization of
acrylonitrile and 2‐acrylamide‐2‐methyl‐1‐propanesulfonic acid in the presence of 1, 4 …
acrylonitrile and 2‐acrylamide‐2‐methyl‐1‐propanesulfonic acid in the presence of 1, 4 …
Polymer-nanodiscs as a novel alignment medium for high-resolution NMR-based structural studies of nucleic acids
Residual dipolar couplings (RDCs) are increasingly used for high-throughput NMR-based
structural studies and to provide long-range angular constraints to validate and refine …
structural studies and to provide long-range angular constraints to validate and refine …
Solid-state NMR methods for the characterization of bioconjugations and protein-material interactions
Protein solid-state NMR has evolved dramatically over the last two decades, with the
development of new hardware and sample preparation methodologies. This technique is …
development of new hardware and sample preparation methodologies. This technique is …
[HTML][HTML] Decomposition of mixed DMPC-aescin vesicles to bicelles is linked to the lipid's main phase transition: A direct evidence by using chain-deuterated lipid
This work investigates the conversion of bicelles into larger sheets or closed vesicles upon
dilution and temperature increase for a system composed of the phospholipid 1, 2 …
dilution and temperature increase for a system composed of the phospholipid 1, 2 …