Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
C Li, YQ Ni, H Xu, QY **ang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies
P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …
life because of its associated complications, including diabetes, cardiovascular diseases …
Adipokine dysregulation and adipose tissue inflammation in human obesity
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
[PDF][PDF] State of the art paper Biochemistry of adipose tissue: an endocrine organ
M Coelho, T Oliveira, R Fernandes - Archives of medical science, 2013 - termedia.pl
Adipose tissue is no longer considered to be an inert tissue that stores fat. This tissue is
capable of expanding to accommodate increased lipids through hypertrophy of existing …
capable of expanding to accommodate increased lipids through hypertrophy of existing …
Inflammation and skeletal muscle wasting during cachexia
JM Webster, LJAP Kempen, RS Hardy… - Frontiers in …, 2020 - frontiersin.org
Cachexia is the involuntary loss of muscle and adipose tissue that strongly affects mortality
and treatment efficacy in patients with cancer or chronic inflammatory disease. Currently, no …
and treatment efficacy in patients with cancer or chronic inflammatory disease. Currently, no …
Forming functional fat: a growing understanding of adipocyte differentiation
Adipose tissue, which is primarily composed of adipocytes, is crucial for maintaining energy
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …
Metabolic regulation of T lymphocytes
NJ MacIver, RD Michalek… - Annual review of …, 2013 - annualreviews.org
T cell activation leads to dramatic shifts in cell metabolism to protect against pathogens and
to orchestrate the action of other immune cells. Quiescent T cells require predominantly ATP …
to orchestrate the action of other immune cells. Quiescent T cells require predominantly ATP …
Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …
and complex endocrine organ, which produces and secretes several adipokines, including …
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
KD Copps, MF White - Diabetologia, 2012 - Springer
The insulin receptor substrate proteins IRS1 and IRS2 are key targets of the insulin receptor
tyrosine kinase and are required for hormonal control of metabolism. Tissues from insulin …
tyrosine kinase and are required for hormonal control of metabolism. Tissues from insulin …
COVID-19 and preexisting comorbidities: risks, synergies, and clinical outcomes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …