Enzyme immobilization on electrospun polymer nanofibers: An overview

ZG Wang, LS Wan, ZM Liu, XJ Huang, ZK Xu - Journal of Molecular …, 2009 - Elsevier
Enzyme immobilization has attracted continuous attention in the fields of fine chemistry,
biomedicine, and biosensor. The performance of immobilized enzyme largely depends on …

Recent trends using natural polymeric nanofibers as supports for enzyme immobilization and catalysis

RS Khan, AH Rather, TU Wani, S Rather… - Biotechnology and …, 2023 - Wiley Online Library
All the disciplines of science, especially biotechnology, have given continuous attention to
the area of enzyme immobilization. However, the structural support made by material …

Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism

AA Walsh, GD Szklarz, EE Scott - Journal of Biological Chemistry, 2013 - ASBMB
Cytochrome P450 (CYP) 1A1 is an extrahepatic monooxygenase involved in the metabolism
of endogenous substrates and drugs, as well as the activation of certain toxins and …

The potential value of natural antioxidative treatment in glaucoma

M Mozaffarieh, MC Grieshaber, S Orgül… - Survey of ophthalmology, 2008 - Elsevier
Glaucomatous optic neuropathy implies loss of retinal ganglion cells, including their axons,
and a major tissue remodeling, especially in the optic nerve head. Although increased …

Structure‐based drug design for cytochrome P450 family 1 inhibitors

Z Dutkiewicz, R Mikstacka - Bioinorganic chemistry and …, 2018 - Wiley Online Library
Cytochromes P450 are a class of metalloproteins which are responsible for electron transfer
in a wide spectrum of reactions including metabolic biotransformation of endogenous and …
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A Kumar, S Roy, S Tripathi… - Journal of Biomolecular …, 2016 - Taylor & Francis
Beta-site APP cleaving enzyme1 (BACE1) catalyzes the rate determining step in the
generation of Aβ peptide and is widely considered as a potential therapeutic drug target for …

Molecular recognition and drug-lead identification: what can molecular simulations tell us?

G Morra, A Genoni, MAC Neves… - Current medicinal …, 2010 - ingentaconnect.com
Molecular recognition and ligand binding involving proteins underlie the most important life
processes within the cell, such as substrate transport, catalysis, signal transmission, receptor …

Covalent Immobilization of Tyrosinase on Electrospun Polyacrylonitrile/Polyurethane/Poly(m-anthranilic acid) Nanofibers: An Electrochemical Impedance Study

U Dagli, Z Guler, AS Sarac - Polymer-Plastics Technology and …, 2015 - Taylor & Francis
Polyacrylonitrile/polyurethane/poly (m-anthranilic acid) nanofibers were fabricated by
electrospinning. Tyrosinase immobilization was performed by EDC/N-hydroxyl succinimide …

Ensemble Modeling of Substrate Binding to Cytochromes P450:  Analysis of Catalytic Differences between CYP1A Orthologs,

JC Prasad, JV Goldstone, CJ Camacho, S Vajda… - Biochemistry, 2007 - ACS Publications
A novel application of modeling and docking approaches involving ensembles of homology
models is used to understand structural bases underlying subtle catalytic differences …

L-Dopa synthesis catalyzed by tyrosinase immobilized in poly (ethyleneoxide) conducting polymers

HB Yildiz, S Caliskan, M Kamaci, A Caliskan… - International journal of …, 2013 - Elsevier
1-3, 4-Dihydroxy phenylalanine called as l-Dopa is a precursor of dopamine and an
important neural message transmitter and it has been a preferred drug for the treatment of …