The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

Background: There is a growing liberalization of cannabis-based preparations for medical
and recreational use. In multiple instances, anxiety and depression are cited as either a …

Ketamine is used clinically as an anaesthetic and a fast-acting antidepressant, and
recreationally for its dissociative properties, raising concerns of addiction as a possible side …

Objective: This review consists of three parts, representing three different possibilities of
interactions between cannabinoid receptor ligands of both exogenous and endogenous …

The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

CB 1 cannabinoid receptors appear to mediate most, if not all of the psychoactive effects of
delta-9-tetrahydrocannabinol and related compounds. This G protein-coupled receptor has …

In this review we will critically assess the hypothesis that the reinforcing effect of virtually all
drugs of abuse is primarily dependent on activation of the mesolimbic dopamine system …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …